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RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae)

The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of the...

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Data Correlations | 1,464 studies

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Tissues category icon Normal tissues
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Zygote 100 100
Femur 76 76
Superior cervical ga… 73 73
Set of fingers 72 72
Superior surface of … 71 71
Blastocyst 69 69
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Compounds category icon Compounds
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Ganciclovir 100 100
Aflatoxin B 99 99
Ioversol 96 96
Conjugated Linoleic … 88 88
Crystalbumins 88 88
Alpha-aminoisocaproi… 86 86
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Diseases category icon Diseases
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Breast cancer 100 100
Acute HIV infection 100 100
Smallpox 98 98
Congenital absence o… 97 97
Acute lymphoid leuke… 96 96
Asymptomatic human i… 96 96
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Individual Studies

  • Gene expression profile of PDGF-treated neural stem cells

    score: 100100 | Mus musculus Mus musculus | RNA Expression   RNA Expression

    Gene expression in neural stem cells that were grown in the presence of FGF-2 to that of cells cultured with PDGF-AA or in the absence of growth factor, which induces differentiation.

    Authors: Demoulin Jean-Baptiste, Enarsson Mia, Essaghir Ahmed et al.

    Organization: Universite Catholique de Louvain MEXP un…

  • Formation of human memory B cells in vitro

    score: 100100 | Homo sapiens Homo sapiens | RNA Expression   RNA Expression

    Determine the expression pattern of in vitro cultured human centrocytes, plasma and memory B cells.

    Authors: Kuo C Tracy, Shaffer L Arthur, Haddad Joseph et al.

    Organization: Columbia University 701 W.168th Street, …
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Associated Researchers

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Thought leaders and organizations working on research involving RAD51.

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  • Patrick Sung
  • Lumir Krejci
  • Hannah Klein
  • Ashok R Venkitaraman
  • Michael G Sehorn
View All Clinical trial sponsors icon Clinical Trials Sponsors
  • SuperGen
  • Barbara Ann Karmanos Cancer Institute
  • Vanderbilt-Ingram Cancer Center
View All Affiliations icon Organizations
  • Yale University School of Medicine
  • University of California
  • University of Oxford
  • Lawrence Berkeley National Laboratory
  • Waseda University

Clinical Trials | 5 trials

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Community

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