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proteasome (prosome, macropain) subunit, beta type, 7

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is...

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Data Correlations | 1,539 studies

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Tissues category icon Normal tissues
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Cardia of stomach 100 100
Penis 95 95
Cecum 94 94
Appendix 86 86
Trigeminal ganglion 86 86
Bronchus 85 85
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Compounds category icon Compounds
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4-hydroxynonenal 100 100
Acetylcysteine 91 91
Dipyridamole 91 91
Oxymetholone 86 86
N-formylmethionine L… 86 86
Cp 63956 86 86
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Diseases category icon Diseases
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Patau's syndrome 100 100
Corneal burn 98 98
alpha-1-Antitrypsin … 96 96
cancer of hypopharyn… 94 94
Abdominal aortic ane… 94 94
Teratozoospermia 91 91
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Individual Studies

  • Heart, liver, muscle and adipose tissue from mice on standard, high calorie, or resveratrol diet

    score: 100100 | Mus musculus Mus musculus | RNA Expression   RNA Expression

    Male C57BL/6NIA mice at one year of age, mice were fed a Standard Diet every day or Every other day (EOD) as well groups fed a standard diet plus 0.01% or 0.04% resveratrol for the duration of the study. Three separate groups were placed on an High Calorie diet (modified by the addition of hydrogena…

    Authors: Pearson J Kevin, Baur A Joseph, Lewis N Kaitlyn et al.

    Organization: National Institute on Aging, NIH Researc…

  • Cellular responses to 4-hydroxy-2-nonenal (HNE)

    score: 100100 | Homo sapiens Homo sapiens | RNA Expression   RNA Expression

    Cellular responses to 4-hydroxy-2-nonenal (HNE)--dose response and time course--three replicate experiments for each treatment

    Authors: West JD, Marnett LJ

    Organization: Vanderbilt University Biochemistry Lawre…
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Associated Researchers

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Thought leaders and organizations working on research involving PSMB7.

View All Author iconAuthors
  • Markus Moser
  • Reinhard Fässler
  • Peter A Keyel
  • Linton M Traub
  • Robyn Roth
View All Affiliations icon Organizations
  • Stanford University School of Medicine
  • Brigham and Women's Hospital
  • Max Planck Institute of Biochemistry
  • Joint Research Laboratory of the Hungarian Academy of Sciences and the…
  • University of Illinois College of Medicine

Community

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