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polymerase (RNA) II (DNA directed) polypeptide C, 33kDa
This gene encodes the third largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a cysteine rich region and exists as a heterodimer with another polymerase subunit, POLR2J. These two subunits form a core subassembly unit of the polymerase. A pseudogene has been identified on chromosome 21. [provided by RefSeq]
Normal tissues
|
|
||
|---|---|---|---|
| Zygote |
100
|
||
| Lateral nuclear grou… |
79
|
||
| Subdivision of globu… |
79
|
||
| Cecum |
79
|
||
| Caudate nucleus |
78
|
||
| Subdivision of subst… |
78
|
Compounds
|
|
||
|---|---|---|---|
| Cp 63956 |
100
|
||
| Nickel [nickel And N… |
81
|
||
| Haemophilus Influenz… |
78
|
||
| Nsc618084 |
77
|
||
| Actinomycin |
77
|
||
| Androstanolone |
69
|
 Individual Studies |
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|---|---|
|
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Mus musculus
|
RNA Expression
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RNA polymerase II: just stopping by.
Authors: Matthew C Lorincz, Dirk Schübeler
Cell 2007 Jul 13 -
Backtracking determines the force sensitivity of RNAP II in a factor-dependent manner.
Authors: Eric A Galburt, Stephan W Grill, Anna Wiedmann, Lucyna Lubkowska, Jason Choy, Eva Nogales, Mikhail Kashlev, Carlos Bustamante
Nature 2007 Apr 12
Thought leaders and organizations working on research involving POLR2C.
- Jesper Q Svejstrup
- Stephen Buratowski
- Ali Shilatifard
- Danny Reinberg
- Patrick Cramer
- Cancer Research UK London Research Institute
- Harvard Medical School
- University of California
- University of Medicine and Dentistry of New Jersey
- Cornell University
Community
Eric Paquet
Bioinformatician
CRHDQ
Associate Clinical Professor
Chao Family Comprehensive Cancer Center
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