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pregnancy-associated plasma protein A, pappalysin 1
This gene encodes a secreted metalloproteinase which cleaves insulin-like growth factor binding proteins (IGFBPs). It is thought to be involved in local proliferative processes such as wound healing and bone remodeling. Low plasma level of this protein has been suggested as a biochemical marker for pregnancies with aneuploid fetuses. [provided by RefSeq]
Normal tissues
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| Appendix |
100
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| Smooth muscle tissue |
97
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| Placenta |
97
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| Vomeronasal organ |
95
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| Femur |
95
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| Epidermis |
94
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 Individual Studies |
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Mus musculus
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RNA Expression
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Neutralizing antibodies derived from the B cells of 1918 influenza pandemic survivors.
Authors: Xiaocong Yu, Tshidi Tsibane, Patricia A McGraw, Frances S House, Christopher J Keefer, Mark D Hicar, Terrence M Tumpey, Claudia Pappas, Lucy A Perrone, Osvaldo Martinez,…
Nature 2008 Sep 25 -
An ARS element inhibits DNA replication through a SIR2-dependent mechanism.
Authors: Amber Crampton, FuJung Chang, Donald L Pappas, Ryan L Frisch, Michael Weinreich
Molecular cell 2008 Apr 25
Thought leaders and organizations working on research involving PAPPA.
- Mycoses Study Group
- Children's Hospital Boston
- National Cancer Institute (NCI)
- Acorn Cardiovascular, Inc.
- Link America, Inc.
- Aristotle University of Thessaloniki
- Texas Tech University
- Carleton University
- Institute of Continuing Medical Education of Ioannina
- Van Andel Research Institute
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Randomized Study of Caspofungin Prophylaxis Followed by Pre-Emptive Therapy for Invasive Candidiasis in the ICU
conditions: Invasive Fungal Infections
interventions: Caspofungin ; Normal Saline
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Vitamin D Levels in Children With IBD
conditions: Inflammatory Bowel Disease ; Crohn's Disease ; Ulcerative Colitis
interventions: ergocalciferol ; Cholecalciferol
Community
Styliani Pappa
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