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NK3 homeobox 1

The homeodomain-containing transcription factor NKX3-1 is a putative prostate tumor suppressor that is expressed in a largely prostate-specific and androgen-regulated manner. Loss of NKX3-1 protein expression is a common finding in human prostate carcinomas and prostatic intraepithelial neoplasia.[supplied by OMIM]

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Data Correlations | 936 studies

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Tissues category icon Normal tissues
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Bronchus 100 100
Superior surface of … 96 96
Mucosa of pharynx 85 85
Salivary gland 78 78
Adrenal cortex 77 77
Tongue 74 74
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Compounds category icon Compounds
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Lbh-589 100 100
Metribolone 99 99
Suberanilohydroxamic… 94 94
Androstanolone 87 87
Trichostatin A 84 84
Butyric Acid, Sodium… 74 74
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Diseases category icon Diseases
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Male genital organ d… 100 100
cancer of urinary tr… 99 99
Staphylococcus aureu… 99 99
Inflammatory carcino… 93 93
Cicatrization 90 90
Keloid 90 90
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Individual Studies

  • Mouse Phenotypes - Neoplasms

    score: 100100 | Mus musculus Mus musculus | Mutations/Phenotypic   Mutations/Phenotypic

    This study contains curated mouse gene mutation data extracted from the Mouse Genome Database (MGD) at The Jackson Laboratory, Bar Harbor, Maine. Additional computational processing and curation of mouse phenotype data was performed to further organize and group data from related phenotypes into uni…

    Source: NextBio Library/Mutation and Phenotypic data

  • Expression profile of HDAC treated LNCaP cells

    score: 100100 | Homo sapiens Homo sapiens | RNA Expression   RNA Expression

    Genome wide expression changes in LNCaP cells following treatment with the HDACs (Histone Deacetylase Inhibitor) CG-1521 (7.5uM) or TSA (Trichostatin A)

    Authors: Roy S, Jeffrey R, Tenniswood M

    Organization: University of Notre Dame Biological Scie…
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Associated Researchers

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Thought leaders and organizations working on research involving NKX3-1.

View All Author iconAuthors
  • Edward P Gelmann
  • Cory Abate-Shen
  • Michael M Shen
  • Xuesong Ouyang
  • Whitney A Banach-Petrosky
View All Clinical trial sponsors icon Clinical Trials Sponsors
  • University Hospital, Aker
  • Roswell Park Cancer Institute
View All Affiliations icon Organizations
  • Georgetown University
  • University of Medicine and Dentistry of New Jersey-Robert Wood Johnson…
  • Columbia University
  • University of Medicine and Dentistry
  • Georgetown University School of Medicine

Clinical Trials | 2 trials

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