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nuclear factor I/A

Nuclear factor I (NFI) proteins constitute a family of dimeric DNA-binding proteins with similar, and possibly identical, DNA-binding specificity. They function as cellular transcription factors and as replication factors for adenovirus DNA replication. Diversity in this protein family is generated by multiple genes, differential splicing, and heterodimerization.[supplied by OMIM]

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Data Correlations | 1,794 studies

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Tissues category icon Normal tissues
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Great saphenous vein 100 100
Fundus of stomach 92 92
Subdivision of nucle… 87 87
Esophagus 86 86
Tongue 85 85
Peritoneum 85 85
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Compounds category icon Compounds
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Merbromin 100 100
Nchembio.95-comp18 100 100
Methylglyoxal 91 91
Tetanus Toxin 89 89
Trichloroethene 88 88
Flucloxacillin 87 87
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Diseases category icon Diseases
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Acute erythremic mye… 100 100
N2 96 96
Primary malignant cl… 95 95
Abdominal aortic ane… 94 94
Cervix Cancer 92 92
Frontotemporal degen… 91 91
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Individual Studies

  • Dominant negative PPAR gamma expression in primary aortic endothelial cells

    score: 100100 | Mus musculus Mus musculus | RNA Expression   RNA Expression

    Two naturally occurring mutations (P467L, V290M) in the ligand binding domain of PPAR gamma have been described in humans that lead to severe insulin resistance and hypertension. We studied the expression profile in primary aortic endothelial cells in response to endothelial cell specific expression…

    Authors: Keen L Henry, Sigmund D Curt, Beyer M Andreas et al.

    Organization: University of Iowa Internal Medicine Dr.…
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Associated Researchers

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Thought leaders and organizations working on research involving NFIA.

View All Author iconAuthors
  • Ludwine Messiaen
  • Thomas De Raedt
  • Eric Legius
  • Ophélia Maertens
  • Hilde Brems
View All Clinical trial sponsors icon Clinical Trials Sponsors
  • University Hospital, Limoges
View All Affiliations icon Organizations
  • University of California
  • Ghent University Hospital
  • Cardiff University
  • Catholic University Leuven
  • San Giovanni Rotondo and CSS-Mendel Institute

Community

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