RESEARCH
PUBLICATIONS
NEXTBIO COMMUNITY
myosin VIIA
This gene is a member of the myosin gene family. Myosins are mechanochemical proteins characterized by the presence of a motor domain, an actin-binding domain, a neck domain that interacts with other proteins, and a tail domain that serves as an anchor. This gene encodes an unconventional myosin with a very short tail. Defects in this gene are associated with the mouse shaker-1 phenotype and the human Usher syndrome 1B which are characterized by deafness, reduced vestibular function, and (in human) retinal degeneration. Alternative splicing results in multiple transcript variants. [provided by RefSeq]
Normal tissues
|
|
||
|---|---|---|---|
| Adrenal gland |
100
|
||
| Adrenal cortex |
92
|
||
| Salivary gland |
85
|
||
| Femur |
83
|
||
| Epidermis |
83
|
||
| Thyroid gland |
82
|
Compounds
|
|
||
|---|---|---|---|
| Naphthammonum |
100
|
||
| Tanespimycin |
76
|
||
| Piromidic Acid |
74
|
||
| Lipofectamine |
73
|
||
| Ribonucleic Acid |
72
|
||
| Double-stranded Dna |
67
|
 Individual Studies |
|
|---|---|
|
|
Mus musculus
|
Mutations/Phenotypic
Homo sapiens
|
RNA Expression
-
Mutation spectrum of MYO7A and evaluation of a novel nonsyndromic deafness DFNB2 allele with residual function.
Authors: Saima Riazuddin, Sabiha Nazli, Zubair M Ahmed, Yi Yang, Fareeha Zulfiqar, Rehan S Shaikh, Ahmed U Zafar, Shaheen N Khan, Farooq Sabar, Fouzia T Javid,…
Human mutation 2008 Apr -
Usher syndromes due to MYO7A, PCDH15, USH2A or GPR98 mutations share retinal disease mechanism.
Authors: Samuel G Jacobson, Artur V Cideciyan, Tomas S Aleman, Alexander Sumaroka, Alejandro J Roman, Leigh M Gardner, Haydn M Prosser, Monalisa Mishra, N Torben Bech-Hansen, Waldo Herrera,…
Human molecular genetics 2008 Aug 1
Thought leaders and organizations working on research involving MYO7A.
- Institut Pasteur
- UCSD School of Medicine
- University of Pennsylvania
- Duke University Medical Center
- University of California
