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A chronic inflammatory connective tissue disease marked by skin rashes, joint pain and swelling, inflammation of the kidneys, inflammation of the fibrous tissue surrounding the heart (i.e., the pericardium), as well as other problems. Not all affected individuals display all of these problems. Also called systemic lupus erythematosus.

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Data Correlations | 9 studies

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Genes category icon Genes
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FCGR2A 100 100
GADD45A 100 100
CDKN1A 100 100
RASGRP1 100 100
FAS 100 100
DEF6 100 100
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Biogroups category icon Biogroups
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Cell Cycle 100 100
Hematopoietic Cell Lineage 100 100
Hemoglobin's Chaperone 99 99
Immunoglobulin Protein Family 98 98
Immunoglobulin subtype 98 98
chr1p 98 98
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Individual Studies

  • Blood Leukocyte Microarrays to Diagnose Systemic Onset Juvenile Idiopathic Arthritis

    Homo sapiens Homo sapiens | RNA Expression   RNA Expression

    Systemic onset Juvenile Idiopathic Arthritis (SoJIA) represents up to 20% of Juvenile Idiopathic Arthritis (JIA). We have previously reported that this disease is Interleukin 1 (IL1)-mediated, and that IL-1 blockade results in clinical remission in the majority of patients. The diagnosis of SoJIA, h…

    Authors: Allantaz F, Chaussabel D, Stichweh D et al.

    Organization: Baylor Institute for Immunology Research…

  • Mouse Phenotypes - Autoimmune disease

    Mus musculus Mus musculus | Mutations/Phenotypic   Mutations/Phenotypic

    This study contains curated mouse gene mutation data extracted from the Mouse Genome Database (MGD) at The Jackson Laboratory, Bar Harbor, Maine. Additional computational processing and curation of mouse phenotype data was performed to further organize and group data from related phenotypes into uni…

    Source: NextBio Library/Mutation and Phenotypic data
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Associated Researchers

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Thought leaders and organizations working on research involving Lupus.

View All Author iconAuthors
  • Timothy W Behrens
  • Timothy J Vyse
  • Marta E Alarcón-Riquelme
  • Peter K Gregersen
  • Robert R Graham
View All Clinical trial sponsors icon Clinical Trials Sponsors
  • National Institute of Arthritis and Musculoskeletal and Skin Diseases …
  • National Center for Research Resources (NCRR)
  • National Institute of Allergy and Infectious Diseases (NIAID)
  • MedImmune LLC
  • University of California, San Francisco
View All Affiliations icon Organizations
  • Oklahoma Medical Research Foundation
  • Broad Institute of Harvard and Massachusetts Institute of Technology
  • Scripps Research Institute
  • University of California, San Francisco
  • University Hospital Erlangen

Clinical Trials | 1,282 trials

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News | 244 stories

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Community

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View All NextBio Users | 4 people
  • Knut  Wittkowski

    Head, Biostatistics, Epidemiology, and Research Design

    The Rockefeller University Center for Clinical and Translational Science

  • Shiuh-Bin  Fang

    Dr

    Centre for Paediatric Gastroenterology, Royal Free & University College Medical School

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