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v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Normal tissues
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|---|---|---|---|
| Hemisphere of cerebe… |
100
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| Zygote |
99
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| Thyroid gland |
99
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| Cecum |
98
|
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| Femur |
96
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| Vermis of cerebellum |
94
|
Compounds
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|
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|---|---|---|---|
| Sorafenib |
100
|
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| Imatinib |
100
|
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| U 0126 |
78
|
||
| Zinc Ion |
74
|
||
| Ehna |
74
|
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| Particulates Not Oth… |
69
|
Diseases
|
|
||
|---|---|---|---|
| Mastocytosis |
100
|
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| Piebaldism |
100
|
||
| Squamous cell carcin… |
100
|
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| Gastrointestinal str… |
100
|
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| Germ cell tumor |
99
|
||
| Neoplasm of testis |
98
|
 Individual Studies |
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|---|---|
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Mus musculus
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Mutations/Phenotypic
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Innate production of T(H)2 cytokines by adipose tissue-associated c-Kit(+)Sca-1(+) lymphoid cells.
Authors: Kazuyo Moro, Taketo Yamada, Masanobu Tanabe, Tsutomu Takeuchi, Tomokatsu Ikawa, Hiroshi Kawamoto, Jun-Ichi Furusawa, Masashi Ohtani, Hideki Fujii, Shigeo Koyasu
Nature 2010 Jan 28 -
A new twist in the transmembrane signaling tool-kit.
Authors: Mark A Lemmon, Kathryn M Ferguson
Cell 2007 Jul 27
Thought leaders and organizations working on research involving KIT.
- Centers for Disease Control and Prevention
- Sheba Medical Center
- European Organization for Research and Treatment of Cancer
- Bayer HealthCare, Diabetes Care
- Taichung Veterans General Hospital
- Stanford University School of Medicine
- Indiana University School of Medicine
- University of Hong Kong
- University of California
- University of Texas M.D. Anderson Cancer Center
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Evaluation of the A1CNow+ Test Kit
conditions: Diabetes
interventions: A1c Test Kit
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Development of Tuberculosis Diagnostic Kit
conditions: Tuberculosis ; Lung Cancer ; Pneumonia
interventions: none
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Affymetrix, Asuragen Team on MDx Kits
GenomeWeb. - February 18, 2010 -
Rapiddrugdetection.com provides breathalyzer kits for organizations
PR-inside.com. - February 09, 2010
Community
Kit Lau
Kit Thompson
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