NextBio

Help

killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytop...

View Complete Description



Data Correlations | 3 studies

Help for Data Correlations View All
Diseases category icon Diseases
Score Help
Acquired immunodeficiency syndrome 100 100
Systemic inflammatory response synd… 72 72
View Top Diseases
Compounds category icon Compounds
Score Help
Gemcitabine 100 100
View Top Compounds

Individual Studies

  • OMIM - Unspecified immunity deficiency

    score: 100100 | Homo sapiens Homo sapiens | Mutations/Phenotypic   Mutations/Phenotypic

    This study contains curated human phenotype data extracted from OMIM. Additional computational processing and curation of the phenotype data was performed to further organize and group data from related phenotypes into unifying disease categories.

    Source: NextBio Library/Mutation and Phenotypic data
View All Individual Studies

Associated Researchers

Help for Associated Researchers

Thought leaders and organizations working on research involving KIR3DS1.

View All Author iconAuthors
  • Mary Carrington
  • Maureen P Martin
  • Peter Parham
  • Derek Middleton
  • Douglas F Nixon
View All Clinical trial sponsors icon Clinical Trials Sponsors
  • Assistance Publique - Hôpitaux de Paris
View All Affiliations icon Organizations
  • University of California
  • Stanford University School of Medicine
  • Shandong University
  • Kyoto Prefectural University of Medicine
  • Memorial Sloan-Kettering Cancer Center

Clinical Trials | 1 trial

Help for Clinical Trials View All

Community

Help for Community
NextBio Users

  • No NextBio users were found for “KIR3DS1”.
    Complete your user profile with your interests, if you want others to find you within the NextBio community.

NextBio Groups

  • No NextBio groups were found for “KIR3DS1”.
    Be the first to start a group and share your interests with others within the NextBio community.

© 2010 NextBio