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integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)

The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. [provided by RefSeq]

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Data Correlations | 1,297 studies

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Tissues category icon Normal tissues
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Superior cervical ga… 100 100
Thyroid gland 98 98
Great saphenous vein 89 89
Globus pallidus 85 85
Adrenal cortex 83 83
Tongue 82 82
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Compounds category icon Compounds
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Tirofiban 100 100
Ethoxyfen 100 100
Fosfosal 60 60
Benzenetriol 57 57
Triflusal 55 55
Dimethyl Sulfoxide 51 51
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Diseases category icon Diseases
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Thrombasthenia 100 100
Chronic fatigue synd… 78 78
Gp B streptococcal s… 68 68
Bacterial arthritis 66 66
Pyoderma gangrenosum 66 66
Juvenile rheumatoid … 63 63
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Individual Studies

  • Mouse Phenotypes - Inherited platelet disorder

    score: 100100 | Mus musculus Mus musculus | Mutations/Phenotypic   Mutations/Phenotypic

    This study contains curated mouse gene mutation data extracted from the Mouse Genome Database (MGD) at The Jackson Laboratory, Bar Harbor, Maine. Additional computational processing and curation of mouse phenotype data was performed to further organize and group data from related phenotypes into uni…

    Source: NextBio Library/Mutation and Phenotypic data

  • OMIM - Thrombocytopathy

    score: 100100 | Homo sapiens Homo sapiens | Mutations/Phenotypic   Mutations/Phenotypic

    This study contains curated human phenotype data extracted from OMIM. Additional computational processing and curation of the phenotype data was performed to further organize and group data from related phenotypes into unifying disease categories.

    Source: NextBio Library/Mutation and Phenotypic data
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Associated Researchers

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Thought leaders and organizations working on research involving ITGB3.

View All Author iconAuthors
  • Timothy A Springer
  • Reinhard Fässler
  • Bing-Hao Luo
  • Clare L Abram
  • Michael P Sheetz
View All Clinical trial sponsors icon Clinical Trials Sponsors
  • Jagiellonian University
View All Affiliations icon Organizations
  • University of California
  • Max Planck Institute of Biochemistry
  • Harvard Medical School
  • Beatson Institute for Cancer Research
  • Weizmann Institute of Science

Clinical Trials | 1 trial

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Community

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