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interferon regulatory factor 5

This gene encodes a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Alternative splice variants encoding different isoforms exist. [provided by RefSeq]

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Data Correlations | 1,151 studies

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Tissues category icon Normal tissues
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Mesenteric lymph nod… 100 100
Femur 76 76
B lymphoblast 75 75
Epidermis 74 74
B lymphocyte 73 73
Caudate nucleus 73 73
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Compounds category icon Compounds
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Epitiostanol 100 100
Haemophilus Influenz… 100 100
Hydrastine Hydrochlo… 92 92
Harpagoside 90 90
Clotrimazole 89 89
Bicalutamide 85 85
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Diseases category icon Diseases
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Alagille syndrome 100 100
Gastrointestinal str… 77 77
Sjogren's syndrome 72 72
Nephrotoxic acute re… 69 69
Drug toxicity 67 67
Urinary tract infect… 67 67
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Individual Studies

  • Soft tissue sarcomas

    score: 100100 | Homo sapiens Homo sapiens | RNA Expression   RNA Expression

    Global gene expression profiling of ten extraskeletal myxoid chondrosarcomas and 26 other sarcomas using 42,000 spot cDNA microarrays.

    Authors: Van De Rijn Matt

    Organization: Stanford Microarray Database (SMD) Stanf…

  • Diverse liver drug signatures

    score: 100100 | Rattus norvegicus Rattus norvegicus | RNA Expression   RNA Expression

    These data support the publication titled "Classification of a large micro-array dataset. Algorithm comparison and analysis of drug signatures".

    Authors: Natsoulis Georges, El Ghaoui Laurent, Lanckriet R Gert et al.

    Organization: Iconix Biosciences 325 East Middlefield …
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Associated Researchers

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Thought leaders and organizations working on research involving IRF5.

View All Author iconAuthors
  • Snaevar Sigurdsson
  • Marta E Alarcón-Riquelme
  • Ann-Christine Syvänen
  • Lars Rönnblom
  • Gunnar Alm
View All Affiliations icon Organizations
  • Uppsala University
  • University of Tokyo
  • University of Tsukuba
  • Université Paris-Sud 11
  • Johns Hopkins University School of Medicine

Community

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