HTR4 - NextBio

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Search Term: HTR4 (gene)

Overview

5-hydroxytryptamine (serotonin) receptor 4

This gene is a member of the family of serotonin receptors, which are G protein coupled receptors that stimulate cAMP production in response to serotonin (5-hydroxytryptamine). The gene product is a glycosylated transmembrane protein that functions in both the peripheral and central nervous system to modulate the release of various neurotransmitters. Multiple transcript variants encoding proteins with distinct C-terminal sequences have been described, but the full-length nature of some transcript variants has not been determined. [provided by RefSeq]

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Data Correlations | 784 studies

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Normal tissues

Score

Superior cervical ga…

100

Salivary gland

100

Putamen

100

Caudate nucleus

100

Adrenal gland

Bronchus

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Compounds

Score

Htf 919

100

Cisapride

100

Oxfendazole

Hexachlorophene

Venlafaxine

Nomifensine

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Diseases

Score

Conn syndrome

100

Gonorrhea

Fasting diet

Ventilator-associate…

Large granular lymph…

Infectious colitis

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Individual Studies
Drug target sets for approved compounds score: 100 \| Homo sapiens \| Therapeutic The DrugBank database is a unique bioinformatics and cheminformatics resource that combines detailed drug (i.e. chemical, pharmacological and pharmaceutical) data with comprehensive drug target (i.e. sequence, structure, and pathway) information. Authors: David S Wishart, Craig Knox, An Chi Guo et al. Organization: Department of Computing Science, Univers…	Melanocyte with inducible oncogenic receptor Xmrk stimulated with EGF score: 100 \| Mus musculus \| RNA Expression Mouse melanocytes transfected with an inducible version of the oncogenic receptor Xmrk (i.e. HER-mrk), were starved for 72 h and afterwards stimulated with EGF. We compared cells stimulated for 15 minutes, 1 hr, 2 hr, 4 hr, 8 hr or 24 hr, respectively, to unstimulated cells. Source: NextBio Library/Oncology

Individual Studies

Drug target sets for approved compounds

score: 100 | Homo sapiens | Therapeutic

The DrugBank database is a unique bioinformatics and cheminformatics resource that combines detailed drug (i.e. chemical, pharmacological and pharmaceutical) data with comprehensive drug target (i.e. sequence, structure, and pathway) information.

Authors: David S Wishart, Craig Knox, An Chi Guo et al.

Organization: Department of Computing Science, Univers…

Melanocyte with inducible oncogenic receptor Xmrk stimulated with EGF

score: 100 | Mus musculus | RNA Expression

Mouse melanocytes transfected with an inducible version of the oncogenic receptor Xmrk (i.e. HER-mrk), were starved for 72 h and afterwards stimulated with EGF. We compared cells stimulated for 15 minutes, 1 hr, 2 hr, 4 hr, 8 hr or 24 hr, respectively, to unstimulated cells.

Source: NextBio Library/Oncology