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5-hydroxytryptamine (serotonin) receptor 1B

The neurotransmitter serotonin (5-hydroxytryptamine; 5-HT) exerts a wide variety of physiologic functions through a multiplicity of receptors and may be involved in human neuropsychiatric disorders such as anxiety, depression, or migraine. These receptors consist of 4 main groups, 5-HT-1, 5-HT-2, 5-HT-3, and 5-HT4, subdivided into several distinct subtypes on the basis of their pharmacologic characteristics, coupling to intracellular second messengers, and distribution within the nervous system (Zifa and Fillion, 1992 [PubMed 1359584]). The serotonergic receptors belong to the multigene family of receptors coupled to guanine nucleotide-binding ...

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Data Correlations | 553 studies

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Tissues category icon Normal tissues
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Epidermis 100 100
Olfactory epithelium 100 100
Set of pancreatic is… 99 99
Vomeronasal organ 99 99
Trigeminal ganglion 98 98
Salivary gland 98 98
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Compounds category icon Compounds
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Rizatriptan 100 100
Frovatriptan 100 100
Zolmitriptan 100 100
Ergotamin 100 100
Naratriptan 100 100
Sumatriptan 100 100
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Diseases category icon Diseases
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Acute chest syndrome 100 100
Gastric cancer 94 94
Non-secretory myelom… 94 94
Local recurrence of … 91 91
Radiation-induced di… 91 91
Large granular lymph… 90 90
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Individual Studies

  • Drug target sets for approved compounds

    score: 100100 | Homo sapiens Homo sapiens | Therapeutic   Therapeutic

    The DrugBank database is a unique bioinformatics and cheminformatics resource that combines detailed drug (i.e. chemical, pharmacological and pharmaceutical) data with comprehensive drug target (i.e. sequence, structure, and pathway) information.

    Authors: David S Wishart, Craig Knox, An Chi Guo et al.

    Organization: Department of Computing Science, Univers…

  • Effect of high fat and low fat diet on liver expression

    score: 9999 | Mus musculus Mus musculus | RNA Expression   RNA Expression

    Timecourse analysis of the effect high fat and low fat diets have on liver gene expression

    Authors: Alevizos Ilias, Misra Jatin, Stephanopoulos Greg

    Organization: MIT Cambridge 02139 Country USA
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Associated Researchers

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Thought leaders and organizations working on research involving HTR1B.

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  • Yan Shen
  • Qi Xu
  • Alysa E Doyle
  • Rene Hen
  • Jay A Gingrich
View All Clinical trial sponsors icon Clinical Trials Sponsors
  • National Taiwan University Hospital
  • IRCCS San Raffaele
  • National Institute of Mental Health (NIMH)
  • Vanderbilt University
  • Cairo University
View All Affiliations icon Organizations
  • University of Bologna
  • National Food Research Institute
  • First Hospital of Shanxi Medical University
  • University of Washington
  • Bonn University Clinic

Clinical Trials | 7 trials

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Community

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