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K(lysine) acetyltransferase 5

The protein encoded by this gene belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq]

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Data Correlations | 1,081 studies

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Tissues category icon Normal tissues
Score Help
Set of cerebellar pe… 100 100
Subdivision of nucle… 98 98
Pericardium 96 96
Mucosa of mouth 96 96
Caudate nucleus 95 95
Uterine tube 95 95
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Compounds category icon Compounds
Score Help
Humorsol 100 100
Piribedil 95 95
Sulfaquinoxaline 90 90
Suberanilohydroxamic… 87 87
Chloroquine 87 87
Liothyronine I 131 86 86
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Diseases category icon Diseases
Score Help
Pseudopelade 100 100
Adenovirus infection 98 98
Juvenile seronegativ… 96 96
Fracture of femur 94 94
Metastasis from mali… 93 93
Varicella-zoster vir… 92 92
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Individual Studies

  • Drug target sets for approved compounds

    score: 100100 | Homo sapiens Homo sapiens | Therapeutic   Therapeutic

    The DrugBank database is a unique bioinformatics and cheminformatics resource that combines detailed drug (i.e. chemical, pharmacological and pharmaceutical) data with comprehensive drug target (i.e. sequence, structure, and pathway) information.

    Authors: David S Wishart, Craig Knox, An Chi Guo et al.

    Organization: Department of Computing Science, Univers…

  • MRC-5 Lung fibroblast cells treated with rapamycin to study alternative translational routes

    score: 9999 | Homo sapiens Homo sapiens | RNA Expression   RNA Expression

    Anti-cancer drugs targeting protein synthesis are confronted by the problem that genes can exploit alternative translational routes. Polysomes were isolated from MRC-5 cells treated with rapamycin and compared to polysomes from untreated controls to investigate these routes.

    Source: NextBio Library/Pharmacology and Toxicology
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Associated Researchers

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Thought leaders and organizations working on research involving HTATIP.

View All Author iconAuthors
  • Chiara Gorrini
  • Bruno Amati
  • Massimo Squatrito
  • Satoshi Tashiro
  • Masae Ikura
View All Clinical trial sponsors icon Clinical Trials Sponsors
  • Medical University of Vienna
View All Affiliations icon Organizations
  • European Institute of Oncology
  • Dana-Farber Cancer Institute
  • Nagoya City University Medical School
  • Seoul National University
  • University of California, San Francisco

Clinical Trials | 1 trial

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Community

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NextBio Users

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