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homeobox A10

In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor that may regulate gene expression, morphogenesis, and differentiation. More specifically, it may function in fertility, embryo viability, and regulation of hematopoietic lineage commitment. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq]

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Data Correlations | 916 studies

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Tissues category icon Normal tissues
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Myometrium 100 100
Cervix of uterus 77 77
Synovial membrane of… 72 72
Cecum 71 71
Vagina 70 70
Great saphenous vein 70 70
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Compounds category icon Compounds
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Zinc Ion 100 100
Tenoxicam 90 90
Phosphonofluoridic A… 85 85
Promethazine Hydroch… 80 80
Infliximab 78 78
Lycorine 78 78
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Diseases category icon Diseases
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Cicatrization 100 100
Keloid 100 100
Acute promyelocytic … 94 94
Acute biphenotypic l… 88 88
Endometriosis 88 88
Infection by Shigell… 83 83
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Individual Studies

  • Recurrent molecular genetic abnormalities in T-ALL

    score: 100100 | Homo sapiens Homo sapiens | RNA Expression   RNA Expression

    T-cell acute lymphoblastic leukemia (T-ALL) is mostly characterized by specific chromosomal abnormalities, some occurring in a mutually exclusive manner possibly delineating specific T-ALL subgroups. One subgroup, including MLL-rearranged, CALM-AF10 or inv(7)(p15q34) cases, is characterized by eleva…

    Authors: Meijerink JP, Vlierberghe PV, Grotel MV et al.

    Organization: ErasmusMC Rotterdam-Sophia Children's Ho…

  • expO project: Colorectal Cancer Subset

    score: 100100 | Homo sapiens Homo sapiens | RNA Expression   RNA Expression

    The goal of expO and its consortium supporters is to procure tissue samples under standard conditions and perform gene expression analysis on a clinically annotated set of deidentified tumor samples.

    Source: NextBio Library/Oncology
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Associated Researchers

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Thought leaders and organizations working on research involving HOXA10.

View All Author iconAuthors
  • Hugh S Taylor
  • Xiaolan Fei
  • Honami Naora
  • Wenjun Cheng
  • Z Lu
View All Affiliations icon Organizations
  • Yale University School of Medicine
  • University of Texas M.D. Anderson Cancer Center
  • Lund University Hospital
  • Northwestern University
  • University of Massachusetts Medical School

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