Liver Pharmacology and Xenobiotic Response Repertoire

Rattus norvegicus |   RNA Expression

A definition of RNA expression changes that correlate with liver response programs and an understanding of the similarities and differences in responses to different classes of chemicals would aid in new chemical or drug characterization and add to our understanding of liver biology.

Authors: Natsoulis G, Pearson CI, Gollub J et al.

Organization: Iconix Biosciences 325 E. Middlefield Rd…

Lung cancer cells + dasatinib, imatinib, nilotinib or PD0325901

Homo sapiens |   RNA Expression

A549 human lung cancer cell line was treated with 4 kinase inhibitors for 4 or 20 hours. A dilution series for the compounds was also used.

Source: NextBio Library/Pharmacology and Toxicology