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GTP cyclohydrolase I activity
(biogroup)
NextBio Summary
General Info
Body Atlas
Most Correlated Tissues
Ileum mucosa
Liver
Myeloid cells of peripheral blood
T Lymphocyte (regulatory) of peripheral blood
Monocyte of peripheral blood
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Disease Atlas
Most Correlated Diseases
Classical phenylketonuria
Alpha-1-antitrypsin deficiency
Disorder of digestive system
Hyperphenylalaninemia
Brucellosis
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Pharmaco Atlas
Most Correlated Compounds
Fendiline
ellipticine
Sumatriptan
chloroxylenol
enrofloxacin
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Knockdown Atlas
Most Correlated Gene Perturbations
Stat3
TNRC6C
SKI
ACVR1
SMAD9
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Curated Studies
Most Correlated Studies
Dorsal root ganglia gene expression at 2 days, 2 weeks, and 20 weeks post-spinal nerve ligation
Expression Data from Sod2 null and wild type mouse erythroblasts
Differentiating calvarial osteoblast MC3T3-sc4 cells treated with SAHA
Insulinoma cell line INS1ab overexpressing Pdx1 treated with or without IL-1b
Drug Matrix In Vivo Toxicogenomic Study - Rat Bone Marrow [Codelink]
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Literature
Most Relevant Literature
GTP cyclohydrolase I expression, protein, and activity determine intracellular tetrahydrobiopterin l…
Uncoupling of eNOS causes superoxide anion production and impairs NO signaling in the cerebral micro…
Administration of a low dose of sildenafil for 1 week decreases intrahepatic resistance in rats with…
Hydrogen peroxide stimulates tetrahydrobiopterin synthesis through the induction of GTP-cyclohydrola…
Decrease in tetrahydrobiopterin as a possible cause of nephropathy in type II diabetic rats.
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Clinical Trials
Most Relevant Clinical Trials
There were no clinical trials for GTP cyclohydrolase I activity
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