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fibroblast growth factor 21

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The function of this growth factor has not yet been determined. [provided by RefSeq]

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Data Correlations | 497 studies

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Tissues category icon Normal tissues
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Mucosa of mout… 100 100
Set of pancrea… 97 97
Globus pallidu… 96 96
Coronary arter… 95 95
Duodenum 94 94
Trigeminal gan… 92 92
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Compounds category icon Compounds
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Methylcellulos… 100 100
Ceruletide 82 82
Trilinolein 71 71
Triglycerides 71 71
Perfluorocapry… 68 68
Tricaprin 58 58
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Diseases category icon Diseases
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Social environ… 100 100
Ketogenic diet 82 82
General adapta… 73 73
Insulin resist… 60 60
Gonorrhea 58 58
Pulmonary embo… 57 57
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Individual Studies

  • Livers of Wild-Type and PPARalpha-Null Mice Exposed to Perfluorooctanoic Acid (PFOA)

    score: 100100 | Mus musculus Mus musculus | RNA Expression   RNA Expression

    Wild-type and PPARa-null mice were orally dosed for 7 days with either PFOA (1 or 3 mg/kg), the PPARalpha agonist WY-14,643 (50 mg/kg), or compound vehicle. Gene profiling analysis was conducted on 4 animals per group

    Authors: Rosen B Mitchell, Abbott D Barbara, Wolf C Douglas et al.

    Organization: U.S. EPA Reproductive Toxicology GEEBB 2…

  • Effects of caerulein on Mist1 null pancreas

    score: 9999 | Mus musculus Mus musculus | RNA Expression   RNA Expression

    RNA from pancreases from wild type and Mist null mice were induced with caerulein or saline and compared to identify genes with differential expression which might contribute to pancreatitis.

    Authors: Pin C, Kowalik A

    Organization: The University of Western Ontario/CHRI P…
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Associated Researchers

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Thought leaders and organizations working on research involving FGF21.

View All Author iconAuthors
  • Alexei Kharitonenkov
  • Holly A Bina
  • James D Dunbar
  • Yue-Sheng Li
  • Jing Xu
View All Affiliations icon Organizations
  • Lilly Research Laboratories
  • University of Texas Southwestern Medical Center
  • Karolinska University Hospital
  • Kyoto University Graduate School of Pharmaceutical Sciences
  • Boston University School of Medicine

Community

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