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fatty acid binding protein 2, intestinal
The intracellular fatty acid-binding proteins (FABPs) belong to a multigene family with nearly twenty identified members. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Intestinal fatty acid-binding protein 2 gene contains four exons and is an abundant cytosolic protein in small intestine epithelial cells. This gene has a polymorphism at codon 54 that identified an alan...
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| Cecum |
100
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| Small intestine |
83
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| Duodenum |
65
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| Globus pallidus |
63
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| Colon |
63
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| Adrenal cortex |
59
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|---|---|---|---|
| Cyclandelate |
100
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| Cyproterone Acetate |
90
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| Alfacalcidol |
85
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| Ethylestrenol |
84
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| Azoxymethane |
84
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| Indomethacin |
83
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|---|---|---|---|
| High fat diet |
100
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| Cystic fibrosis |
93
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| Infectious colitis |
92
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| cancer of ileum |
83
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| Helicobacter-associa… |
83
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| Metabolic syndrome X |
83
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Individual Studies |
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Authors: Tony Velkov, James Horne, Aisha Laguerre, Eric Jones, Martin J Scanlon, Christopher J H Porter
Chemistry & biology 2007 AprAuthors: Maja Klapper, Mike Böhme, Inke Nitz, Frank Döring
Human mutation 2008 JanThought leaders and organizations working on research involving FABP2.
conditions: Type 2 Diabetes Mellitus
interventions: none
conditions: Dyslipidemia ; Type 2 Diabetes Mellitus
interventions: sandwich