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dipeptidyl-peptidase 7

The protein encoded by this gene is a post-proline cleaving aminopeptidase expressed in quiescent lymphocytes. The resting lymphocytes are maintained through suppression of apoptosis, a state which is disrupted by inhibition of this novel serine protease. The enzyme has strong sequence homology with prolylcarboxypeptidase and is active at both acidic and neutral pH. [provided by RefSeq]

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Data Correlations | 1,207 studies

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Tissues category icon Normal tissues
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Pituitary gland 100 100
Ganglion of cranial … 97 97
Preoptic area 97 97
Subdivision of subst… 96 96
Coronary artery 96 96
Zygote 95 95
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Compounds category icon Compounds
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Erythromycin 100 100
Digoxin 99 99
Carmustine 98 98
Ethylestrenol 96 96
Sodium Tungstate(vi) 92 92
Adeka Pluronic F 108 91 91
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Diseases category icon Diseases
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Starvation 100 100
Allergy to ragweed p… 96 96
Hypoxic-ischemic bra… 94 94
Fracture of femur 92 92
Condition of fetal g… 92 92
Helicobacter pylori … 92 92
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Individual Studies

  • P. berghei-infected hepatocytes at different times post-infection

    score: 100100 | Mus musculus Mus musculus | RNA Expression   RNA Expression

    Total RNA was extracted from Plasmodium berghei infected mouse hepatocytes at different time points (6,12,18,24 hours post-infection) and compared to uninfected controls.

    Source: NextBio Library/Immune response and infection

  • siRNA mediated repression of Pea3 and Erm in mammary cancerous cells

    score: 100100 | Mus musculus Mus musculus | RNA Expression   RNA Expression

    Mouse mammary cancerous MMT cells (ATCC CCL-51) have been transfected with a siRNA control, an erm-directed siRNA or an pea3-directed siRNA.

    Authors: Firlej Virginie, Ladam Franck, Brysbaert Guillaume et al.

    Organization: CNRS UMR 8161 Institut de Biologie de Li…
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Associated Researchers

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Thought leaders and organizations working on research involving DPP7.

View All Author iconAuthors
  • Simon ScharpĂ©
  • Ingrid De Meester
  • Anne-Marie Lambeir
  • Pieter Van der Veken
  • Koen Augustyns
View All Affiliations icon Organizations
  • University of Antwerp
  • Tufts University School of Medicine
  • University of Szeged
  • Otto-von-Guericke-University Magdeburg
  • Merck Research Laboratories

Community

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