Broad Connectivity Map (CMAP 2.0) compound database

score: 100 | Homo sapiens |   RNA Expression

A reference collection of genome-wide transcriptional expression data from cultured human cells treated with bioactive small molecules that enable the discovery of functional connections between drugs, genes and diseases through the transitory feature of common gene-expression changes.

Authors: Lamb J

Organization: Broad Institute Seven Cambridge Center C…

Lung cancer cells + dasatinib, imatinib, nilotinib or PD0325901

score: 100 | Homo sapiens |   RNA Expression

A549 human lung cancer cell line was treated with 4 kinase inhibitors for 4 or 20 hours. A dilution series for the compounds was also used.

Source: NextBio Library/Pharmacology and Toxicology