DEN-induced hepatocarcinogenesis in c-Met knockout mice

score: 100 | Mus musculus |   RNA Expression

HGF has been reported to have both positive and negative effects on carcinogenesis. Here we show that the loss of c-Met signaling in hepatocytes enhanced rather than suppressed the early stages of chemical hepatocarcinogenesis.

Organization: National Cancer institute/NIH Cellular a…

Hippocampus and cerebral cortex from mice deficient in Cox-1 or Cox-2

score: 98 | Mus musculus |   RNA Expression

We analyzed the overall gene expression from the cortex and hippocampus of COX-1 +/+, COX-1 -/-, COX-2 +/+, COX-2 -/-, and COX-2 +/-.

Authors: Toscano D Christopher, Bosetti Francesca, Prabhu V Vinaykumar et al.

Organization: National Institutes of Health National I…