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discs, large homolog 2 (Drosophila)
This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family. The encoded protein forms a heterodimer with a related family member that may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins. Multiple transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described, but their full-length nature is not known. [provided by RefSeq]
Normal tissues
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|
||
|---|---|---|---|
| Dorsal striatu… |
100
|
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| Substantia nig… |
99
|
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| Inferior gangl… |
96
|
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| Preoptic area |
95
|
||
| Ventral tegmen… |
92
|
||
| Vestibular nuc… |
92
|
Compounds
|
|
||
|---|---|---|---|
| Carbohydrates … |
100
|
||
| Althiazide |
80
|
||
| 2-(3-fluorophe… |
73
|
||
| Liposome |
68
|
||
| Elaidic Acid |
67
|
||
| Retinoic Acid |
67
|
Diseases
|
|
||
|---|---|---|---|
| Fasting diet |
100
|
||
| Streptococcal … |
91
|
||
| Idiopathic thr… |
87
|
||
| Papillary thyr… |
79
|
||
| Pilocytic astr… |
75
|
||
| Adrenal carcin… |
74
|
 Individual Studies |
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|---|---|
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Mus musculus
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RNA Expression
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The PDZ protein MPP2 interacts with c-Src in epithelial cells.
Authors: Martin Baumgartner, Andreas Weiss, Thorsten Fritzius, Jochen Heinrich, Karin Moelling
Experimental cell research 2009 Oct 15 -
Synapse-specific and developmentally regulated targeting of AMPA receptors by a family of MAGUK scaffolding proteins.
Authors: Guillermo M Elias, Lars Funke, Valentin Stein, Seth G Grant, David S Bredt, Roger A Nicoll
Neuron 2006 Oct 19
Thought leaders and organizations working on research involving DLG2.
- Johns Hopkins University School of Medicine
- University of California
- University of Alabama - Birmingham
- University of California, San Francisco
- Massachusetts General Hospital and Harvard Medical School
