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A gastrointestinal disorder characterized by chronic inflammation involving all layers of the intestinal wall, noncaseating granulomas affecting the intestinal wall and regional lymph nodes, and transmural fibrosis. Crohn disease most commonly involves the terminal ileum; the colon is the second most common site of involvement. --2004

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Individual Studies
  • Mouse Phenotypes - Inflammatory disorder of digestive tract

    Mus musculus Mus musculus | Mutations/Phenotypic   Mutations/Phenotypic

    This study contains curated mouse gene mutation data extracted from the Mouse Genome Database (MGD) at The Jackson Laboratory, Bar Harbor, Maine. Additional computational processing and curation of mouse phenotype data was performed to further organize and group data from related phenotypes into uni…

    Source: NextBio Library/Mutation and Phenotypic data

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Thought leaders and organizations working on research involving Crohn's disease.

  • Jack Satsangi
  • Paul Rutgeerts
  • Natalie J Prescott
  • Clive M Onnie
  • Christopher G Mathew
  • National Institute of Allergy and Infectious Diseases (NIAID)
  • Elan Pharmaceuticals
  • Nationwide Children's Hospital
  • Groupe d'Etude Therapeutique des Affections Inflammatoires Digestives
  • Tel-Aviv Sourasky Medical Center
  • University of Oxford
  • Children's Hospital of Philadelphia
  • Christian-Albrechts-University
  • University of California
  • Mayo Clinic

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