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chemokine (C-C motif) ligand 17

This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. The product of this gene binds to chemokine receptors CCR4 and CCR8. This chemokine plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells. [provided by RefSeq]

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Data Correlations | 634 studies

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Tissues category icon Normal tissues
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Caudate nucleus 100 100
Femur 97 97
B lymphocyte 95 95
Salivary gland 94 94
Esophagus 93 93
Nipple 93 93
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Compounds category icon Compounds
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Aicar 100 100
Ovalicin 93 93
Manlam 92 92
Haemophilus Influenz… 76 76
Nickel [nickel And N… 74 74
1,25-dihydroxy-23-ox… 74 74
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Diseases category icon Diseases
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Venous hypertension 100 100
Fluid overload 92 92
Hodgkin disease, nod… 81 81
House dust mite alle… 75 75
Helminthiasis 71 71
Severe combined immu… 69 69
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Individual Studies

  • Daudi cells treated with anti-CD40, IL-4 and AICAR

    score: 100100 | Homo sapiens Homo sapiens | RNA Expression   RNA Expression

    We used microarrays to detail the action of AICAR on the transcriptome response to CD40-ligation and IL-4 stimulation in Daudi cells.

    Authors: Fukasawa Hiroshi, Wakamatsu Toshifumi

    Organization: Institute of Medicinal Molecular Design,…

  • Formation of human memory B cells in vitro

    score: 100100 | Homo sapiens Homo sapiens | RNA Expression   RNA Expression

    Determine the expression pattern of in vitro cultured human centrocytes, plasma and memory B cells.

    Authors: Kuo C Tracy, Shaffer L Arthur, Haddad Joseph et al.

    Organization: Columbia University 701 W.168th Street, …
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Associated Researchers

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Thought leaders and organizations working on research involving CCL17.

View All Author iconAuthors
  • Kunihiko Tamaki
  • Daniel Hebenstreit
  • Hidehisa Saeki
  • Yong-Jun Liu
  • Gerald Wirnsberger
View All Clinical trial sponsors icon Clinical Trials Sponsors
  • Shionogi USA, Inc.
  • Hospices Civils de Lyon
View All Affiliations icon Organizations
  • University of Tokyo
  • University of Salzburg
  • Keio University
  • Benaroya Research Institute
  • University of Groningen

Clinical Trials | 2 trials

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Community

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