A transmissible spongiform encephalopathy of cattle associated with abnormal prion proteins in the brain. Affected animals develop excitability and salivation followed by ATAXIA. This disorder has been associated with consumption of SCRAPIE infected ruminant derived protein. This condition may be transmitted to humans, where it is referred to as variant or new variant CREUTZFELDT-JAKOB SYNDROME. (Vet Rec 1998 Jul 25;143(41):101-5)

Literature | 3,120 results

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• Risk of oral infection with bovine spongiform encephalopathy agent in primates.

  Authors: Corinne Ida Lasmézas, Emmanuel Comoy, Stephen Hawkins, Christian Herzog, Franck Mouthon, Timm Konold, Frédéric Auvré, Evelyne Correia, Nathalie Lescoutra-Etchegaray, Nicole Salès,…

  Lancet 2005 Feb 26-Mar 4

• The origin of bovine spongiform encephalopathy: the human prion disease hypothesis.

  Authors: Alan C F Colchester, Nancy T H Colchester

  Lancet 2005 Sep 3-9

Associated Researchers

Thought leaders and organizations working on research involving Bovine Spongiform Encephalopathy.

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• Thierry Baron
• Anne-Gaëlle Biacabe
• Andreas Zurbriggen
• Torsten Seuberlich
• Anna Bencsik

View All Clinical Trials Sponsors

• Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
• Duke University
• Medical Research Council

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• Agence Française de Sécurité Sanitaire des Aliments
• Veterinary Laboratories Agency
• Centro de Investigación en Sanidad Animal
• National Animal Disease Center
• University of Berne

Clinical Trials | 3 trials

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• PRION-1: Quinacrine for Human Prion Disease

  conditions: Prion Disease

  interventions: Quinacrine

   

• Serum-Free Thymus Transplantation in DiGeorge Anomaly

  conditions: DiGeorge Anomaly

  interventions: Serum Free Thymus Transplantation with Immunosuppression ; Serum Free Thymus Transplantation without immunosuppression

   

News | 3 stories

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• Spongiform brain diseases are caused by aberrant protein, new research shows

  Science Daily. - January 27, 2010

• Study offers evidence that spongiform brain diseases are caused by aberrant protein

  Eurekalert Infectious_emerging_diseases. - January 27, 2010

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