BRIP1 - NextBio

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Search Term: BRIP1 (gene)

Overview

BRCA1 interacting protein C-terminal helicase 1

The protein encoded by this gene is a member of the RecQ DEAH helicase family and interacts with the BRCT repeats of breast cancer, type 1 (BRCA1). The bound complex is important in the normal double-strand break repair function of breast cancer, type 1 (BRCA1). This gene may be a target of germline cancer-inducing mutations. [provided by RefSeq]

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Data Correlations | 830 studies

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Normal tissues

Score

Superior surface of …

100

Viscerocranial mucos…

Vulva

Femur

Penis

Esophagus

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Compounds

Score

Maltobionate

100

Azapropazone

Zardaverine

Zalcitabine

Disopyramide

Prazosin

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Diseases

Score

Fanconi's anemia

100

cancer of lymphoid h…

Breast cancer

Gonorrhea

Congenital absence o…

Smallpox

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Individual Studies
Broad Connectivity Map (CMAP 2.0) compound database score: 100 \| Homo sapiens \| RNA Expression A reference collection of genome-wide transcriptional expression data from cultured human cells treated with bioactive small molecules that enable the discovery of functional connections between drugs, genes and diseases through the transitory feature of common gene-expression changes. Authors: Lamb J Organization: Broad Institute Seven Cambridge Center C…	Cancer census - gene mutations in cancer and other diseases score: 100 \| Homo sapiens \| Mutations/Phenotypic The Cancer Gene Census is an ongoing effort to catalogue those genes for which mutations have been causally implicated in cancer. The original census and analysis was published in Nature Reviews Cancer Authors: P Andrew Futreal, Lachlan Coin, Mhairi Marshall et al. Organization: Cancer Genome Project, Human Genome Anal…

Individual Studies

Broad Connectivity Map (CMAP 2.0) compound database

score: 100 | Homo sapiens | RNA Expression

A reference collection of genome-wide transcriptional expression data from cultured human cells treated with bioactive small molecules that enable the discovery of functional connections between drugs, genes and diseases through the transitory feature of common gene-expression changes.

Authors: Lamb J

Organization: Broad Institute Seven Cambridge Center C…

Cancer census - gene mutations in cancer and other diseases

score: 100 | Homo sapiens | Mutations/Phenotypic

The Cancer Gene Census is an ongoing effort to catalogue those genes for which mutations have been causally implicated in cancer. The original census and analysis was published in Nature Reviews Cancer

Authors: P Andrew Futreal, Lachlan Coin, Mhairi Marshall et al.

Organization: Cancer Genome Project, Human Genome Anal…