Involvement of hCMV in the ontogeny of CD4+ T-LGL

score: 100 | Homo sapiens |   RNA Expression

We investigate the potential involvement of hCMV in the origin and/or expansion of monoclonal CD4+ T-LGL. A detailed characterization of those genes that underwent changes in T-LGL cells responding to hCMV was performed by microarray gene expression profile (GEP) analysis.

Authors: Rodriguez-Caballero A, Garcia-Montero AC, Barcena P et al.

Organization: Cancer Research Center. University of Sa…

Cooperative Signaling in the STAT3 and NF-kB Pathways in Subtypes of diffuse large B cell lymphoma

score: 100 | Homo sapiens |   RNA Expression

Here we show that the NF-kB pathway induces the expression of the cytokines IL-6 and IL-10 in activated B cell-like DLBCL cell lines, which also have high levels of total and phosphorylated STAT3 protein, suggesting autocrine signaling.

Organization: National Cancer Institute Metabolism Bra…