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A progressive, neurodegenerative disease characterized by loss of function and death of nerve cells in several areas of the brain leading to loss of cognitive function such as memory and language.

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Data Correlations | 7 studies

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Genes category icon Genes
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PPP3CA 100 100
KLC1 100 100
PLCB1 100 100
PSEN1 100 100
APP 100 100
APOE 100 100
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Biogroups category icon Biogroups
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Regulation of CK1/CDK5 by Type 1 Gl… 100 100
Long Term Potentiation 100 100
Calcium Signaling Pathway 99 99
Neurotransmitter-gated ion-channel … 98 98
Oxidative Phosphorylation 98 98
NDK Dynamin Pathway 98 98
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Individual Studies

  • Alzheimers disease with and without neurofibrillary tangles

    Homo sapiens Homo sapiens | RNA Expression   RNA Expression

    A better understanding of the mechanisms underlying neurofibrillary tangle formation may help to clarify the basis for dementia of Alzheimer's Disease and other "tauopathies." The expression profiles of both neurons containing neurofibrillary tangles and normal neurons from the entorhinal cortex of…

    Authors: Rogers Joseph

    Organization: NIH Neuroscience Microarray Consortium N…

  • Mouse Phenotypes - Degenerative disease of the CNS

    Mus musculus Mus musculus | Mutations/Phenotypic   Mutations/Phenotypic

    This study contains curated mouse gene mutation data extracted from the Mouse Genome Database (MGD) at The Jackson Laboratory, Bar Harbor, Maine. Additional computational processing and curation of mouse phenotype data was performed to further organize and group data from related phenotypes into uni…

    Source: NextBio Library/Mutation and Phenotypic data
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Associated Researchers

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Thought leaders and organizations working on research involving Alzheimer's disease.

View All Author iconAuthors
  • Seth Love
  • David M Holtzman
  • John Hardy
  • David Mann
  • Didier Hannequin
View All Clinical trial sponsors icon Clinical Trials Sponsors
  • National Institute on Aging (NIA)
  • National Institute of Mental Health (NIMH)
  • Department of Veterans Affairs
  • Molecular NeuroImaging
  • Eli Lilly and Company
View All Affiliations icon Organizations
  • MassGeneral Institute for Neurodegenerative Disease
  • Mayo Clinic College of Medicine
  • Washington University School of Medicine
  • University of California, San Diego
  • Massachusetts General Hospital

Clinical Trials | 944 trials

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