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activating transcription factor 4 (tax-responsive enhancer element B67)

This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, loc...

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Data Correlations | 1,517 studies

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Tissues category icon Normal tissues
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Great saphenous vein 100 100
Medial globus pallid… 93 93
Putamen 92 92
Nucleus accumbens 89 89
Pylorus 88 88
Salivary gland 88 88
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Compounds category icon Compounds
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Iza 100 100
Glutamate 99 99
Meclocycline 80 80
Deferasirox 71 71
Minocycline 70 70
Dequalinium Chloride 66 66
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Diseases category icon Diseases
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Infection by Candida… 100 100
Compression injury o… 97 97
Injury of external e… 96 96
SAIDS 91 91
Coronary occlusion 90 90
Human immunodeficien… 89 89
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Individual Studies

  • Comparison of pure-species Drosophila expression to hybrid expression

    score: 100100 | Homo sapiens Homo sapiens | RNA Expression   RNA Expression

    In this study, we examined and compared patterns of misexpression in sterile F1 male hybrids of Drosophila simulans and 2 of its sibling species, Drosophila mauritiana and Drosophila sechellia, at both the larval and adult life stages.

    Authors: Moehring AJ, Noor MA, Teeter KC

    Organization: Duke University DCMB/Biology Mohamed Noo…

  • Gene Expression Study in WT and ATF4 KO embryonic neurons

    score: 100100 | Mus musculus Mus musculus | RNA Expression   RNA Expression

    To identity of oxidative stress-inducible transcription factors and their role(s) in propagating the death cascade we performed microarray analysis of neurons from ATF4 knockout and wildtype mice undergoing oxidative stress

    Authors: Lange PS, Chavez JC, Pinto JT et al.

    Organization: UCLA Neurology Neurogenetics 695 Charles…
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News | 2 stories

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