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achaete-scute complex homolog 2 (Drosophila)
This gene is a member of the basic helix-loop-helix (BHLH) family of transcription factors. It activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. Involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system. [provided by RefSeq]
Normal tissues
|
|
||
|---|---|---|---|
| Salivary gland |
100
|
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| Small intestine |
94
|
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| Epidermis |
91
|
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| Caudate nucleus |
90
|
||
| Cecum |
90
|
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| Pylorus |
89
|
Compounds
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|
||
|---|---|---|---|
| Azamun [czech] |
100
|
||
| Gelatine |
91
|
||
| 2-acetylaminofluoren… |
88
|
||
| Propylene Glycol Usp |
86
|
||
| Armodafinil |
84
|
||
| Salicylic Acid |
83
|
 Individual Studies |
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|---|---|
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Homo sapiens
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RNA Expression
Mus musculus
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The interval between Ins2 and Ascl2 is dispensable for imprinting centre function in the murine Beckwith-Wiedemann region.
Authors: Louis Lefebvre, Lynn Mar, Aaron Bogutz, Rosemary Oh-McGinnis, Mohammad A Mandegar, Jana Paderova, Marina Gertsenstein, Jeremy A Squire, Andras Nagy
Human molecular genetics 2009 Nov 15 -
Transcription factor achaete scute-like 2 controls intestinal stem cell fate.
Authors: Laurens G van der Flier, Marielle E van Gijn, Pantelis Hatzis, Pekka Kujala, Andrea Haegebarth, Daniel E Stange, Harry Begthel, Maaike van den Born, Victor Guryev, Irma Oving,…
Cell 2009 Mar 6
Thought leaders and organizations working on research involving ASCL2.
- Princeton University
- University of Calgary
- University of Texas Southwestern Medical Center
- National Institute of Genetics
- Asahikawa Medical College
