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angiopoietin 2

The protein encoded by this gene is an antagonist of angiopoietin 1 (ANGPT1) and endothelial TEK tyrosine kinase (TIE-2, TEK). The encoded protein disrupts the vascular remodeling ability of ANGPT1 and may induce endothelial cell apoptosis. Three transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq]

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Data Correlations | 1,022 studies

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Tissues category icon Normal tissues
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Pericardium 100 100
Mesenteric lymph nod… 86 86
Trigeminal ganglion 82 82
Vomeronasal organ 82 82
Ciliary ganglion 71 71
Cecum 71 71
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Compounds category icon Compounds
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Deamino Arginine Vas… 100 100
Catechin L-form 100 100
Lysophosphatidic Aci… 97 97
Interferon Gamma 94 94
Mesatp Cpd 93 93
Crystal Violet 92 92
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Diseases category icon Diseases
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Clear cell carcinoma… 100 100
Anomaly of chromosom… 97 97
Adrenal carcinoma 95 95
Uterine fibroids 93 93
Kaposi's sarcoma 92 92
Renal cell carcinoma 91 91
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Individual Studies

  • Rat brain under hypoxic -ischemia (hypoxic preconditioning)

    score: 100100 | Rattus norvegicus Rattus norvegicus | RNA Expression   RNA Expression

    Hypoxic-ischemic (HI) injury in the developing brain is a common cause of disability in children, and there are no effective treatments at this time.

    Authors: Wilson M

    Organization: NIH Neuroscience Microarray Consortium N…

  • anti-AR siRNA on LNCaP and abl prostate cancer cells

    score: 100100 | Homo sapiens Homo sapiens | RNA Expression   RNA Expression

    We investigated AR-induced gene expression in prostate cancer cells LNCaP and abl by transfecting siAR / siControl or treating cells with androgen (DHT) over a time course.

    Source: NextBio Library/Oncology
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Associated Researchers

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Thought leaders and organizations working on research involving ANGPT2.

View All Author iconAuthors
  • Hans-Peter Hammes
  • Hellmut G Augustin
  • Ulrike Fiedler
  • Urban Deutsch
  • Gavin Thurston
View All Clinical trial sponsors icon Clinical Trials Sponsors
  • Kaohsiung Medical University Chung-Ho Memorial Hospital
  • Instituto Valenciano de Infertilidad, Spain
  • Albert Einstein College of Medicine of Yeshiva University
  • University of Chicago
  • Assaf-Harofeh Medical Center
View All Affiliations icon Organizations
  • Tumor Biology Center
  • University of Heidelberg
  • City Hospital
  • University College London
  • Albert Einstein College of Medicine

Community

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