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anaphase promoting complex subunit 13

This gene encodes a component of the anaphase promoting complex, a large ubiquitin-protein ligase that controls cell cycle progression by regulating the degradation of cell cycle regulators such as B-type cyclins. The encoded protein is evolutionarily conserved and is required for the integrity and ubiquitin ligase activity of the anaphase promoting complex. Pseudogenes and splice variants have been found for this gene; however, the biological validity of some of the splice variants has not been determined. [provided by RefSeq]

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Data Correlations | 1,029 studies

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Tissues category icon Normal tissues
Score Help
Medulla of kidney 100 100
Cortex of kidney 86 86
Adrenal cortex 85 85
Thyroid gland 79 79
Cecum 79 79
Pericardium 78 78
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Compounds category icon Compounds
Score Help
Tnp00204 100 100
Lysophosphatidic Aci… 86 86
Piperacillin 74 74
Mevalonate 71 71
Decamethonium Bromid… 69 69
C00377 67 67
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Diseases category icon Diseases
Score Help
N2 100 100
Diffuse scleroderma 94 94
Morphea 86 86
Thrombosis of renal … 84 84
Cirrhosis of liver 83 83
Haematologic neoplas… 82 82
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Individual Studies

  • Inhibition of DNA methylation and histone deacetylation in hepatoma cells

    score: 100100 | Homo sapiens Homo sapiens | RNA Expression   RNA Expression

    Microarrays were used to study the response to inhibition of DNA methylation and histone deacetylation using HepG2 cells treated with 5-aza-dC, TSA, both, or nothing.

    Authors: Dannenberg O Luke, Edenberg J Howard

    Organization: Indiana University School of Medicine In…

  • Broad Connectivity Map (CMAP 2.0) compound database

    score: 100100 | Homo sapiens Homo sapiens | RNA Expression   RNA Expression

    A reference collection of genome-wide transcriptional expression data from cultured human cells treated with bioactive small molecules that enable the discovery of functional connections between drugs, genes and diseases through the transitory feature of common gene-expression changes.

    Authors: Lamb J

    Organization: Broad Institute Seven Cambridge Center C…
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Associated Researchers

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Thought leaders and organizations working on research involving ANAPC13.

View All Author iconAuthors
  • Ramnik J Xavier
  • Jonas Warringer
  • Tobias Oelschlaegel
  • P San-Segundo
  • C R Vázquez de Aldana
View All Affiliations icon Organizations
  • Universidad de Salamanca/CSIC
  • CSIC/Universidad de Salamanca
  • Max Planck Institute of Molecular Cell Biology and Genetics. Scionics …
  • University of North Carolina
  • Broad Institute of MIT and Harvard

Community

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