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[Obesity and eating disorders] Severe obesity is associated with novel single nucleotide polymorphisms of the ESR1 and PPAR{gamma} locus in Han Chinese
American journal. - July 19, 2009Background: A large number of potential obesity loci have been reported. At least 18 genes have been replicated in a minimum of 5 studies on obesity-related phenotypes. Fourteen additional genes have been associated with obesity in Asians.Objectives: Our objectives were to examine how…
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Time (and PPAR-beta/delta) Heals All Wounds
Science Daily. - March 29, 2009Mammalian skin requires constant maintenance, but how do skin cells know when to proliferate and at what rate? Scientists reveal that skin fibroblasts use a protein called PPAR / to make sure overlying epithelial cells don't proliferate too quickly. Their results highlight how commun…
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What Is The Suppressing Effect Of The PPAR-gamma Ligands On Stomach Cancer Cells?
Medical News Today.PPAR- gamma is manifested in a variety of tissues and cancer cells and the ligands that activate PPAR- PPAR- are currently being studied as a novel treatment. The PPAR-gamma ligand generally decreases the survival rate of cancer cells via differentiation, apoptotic induction, and chan…
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Pulmonary Hypertension In Children May Result From Reduced Activity Of Gene Regulator
Science Daily. - March 13, 2009Too little activity by gene regulators called PPARs appears to be a major player in the irreversible lung damage that can occur in children with heart defects, researchers say.
