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Circulating endothelial cells play a fundamental role in the development of cancer in children
News-Medical. - September 01, 2009Endothelial progenitor cells may play a role in the start and progression of metastatic disease in children with cancer, according to study results published in Clinical Cancer Research, a journal of the American Association for Cancer Research.
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Endothelial Cells Linked to Metastatic Cancer in Kids (CME/CE)
MedPageToday.com. - July 15, 2009HOUSTON (MedPage Today) -- Metastasis of pediatric cancers may have its origin in activities related to circulating endothelial progenitor cells, according to investigators who identified the association.
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Neuropilin-1/GIPC1 Signaling Regulates A5b1 Integrin Traffic And Function In Endothelial Cells
Medical News Today.Neuropilin 1 (Nrp1) is a coreceptor for vascular endothelial growth factor A165 (VEGF-A165, VEGF-A164 in mice) and semaphorin 3A (SEMA3A). Nevertheless, Nrp1 null embryos display vascular defects that differ from those of mice lacking either VEGF-A164 or Sema3A proteins. Furthermore, …
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Common infant tumour has a Nox(4)ious requirement
Science Centric. - July 14, 2009Haemangiomas are the most common tumour of infancy. They are benign tumours derived from cells that line blood vessels (endothelial cells) and spontaneously regress as a child gets older...
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Effect of Habitual Aerobic Exercise on Body Weight and Arterial Function in Overweight and Obese Men
American journal. - September 14, 2009The effect of habitual exercise on vascular function, including central arterial distensibility and endothelial function, in obese subjects has not yet been clarified. We investigated whether aerobic exercise training affects central arterial distensibility and endothelial function in…
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Blood-Borne Molecule Helps Regulate Blood-Vessel Integrity
Medical News Today. - June 17, 2009Although maintaining the integrity of blood vessel walls is essential for life, well-controlled temporary leakage of blood contents through the walls of blood vessels into the tissues is a hallmark of inflammation. Although the molecule S1P is known to act on the cells that line blood…
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Polymorphism In Endostatin, An Angiogenesis Inhibitor, And Prostate Cancer Risk And Survival: A Prospective Study
Medical News Today. - May 26, 2009UroToday.com - Angiogenesis is the process of new blood vessel formation in tumors, facilitating their growth. Endostatin is a cleavage product of collagen and is a potent inhibitor of endothelial cell proliferation and migration. Endostatin causes apoptosis in endothelial and tumor c…
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Comparison of the Effects of Ramipril Versus Telmisartan on High-Sensitivity C-Reactive Protein and Endothelial Progenitor Cells After Acute Coronary Syndrome
American journal. - May 31, 2009To compare the anti-inflammatory and endothelial progenitor cell mobilizing effects of ramipril and telmisartan in patients presenting with acute coronary syndrome (ACS), 42 patients with ACS were randomized after successful percutaneous coronary intervention to ramipril 5 mg/day (22 …
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[Seminar] Renal cell carcinoma
Lancet. - March 26, 2009Considerable progress has been made in the treatment of patients with renal cell carcinoma, with innovative surgical and systemic strategies revolutionising the management of this disease. In localised disease, partial nephrectomy for small tumours and radical nephrectomy for large tu…
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Lack Of VEGF Can Cause Defects Similar To Dry Macular Degeneration
Science Daily. - November 12, 2009Scientists have found that when the eye is missing a diffusible form of vascular endothelial growth factor (VEGF), i.e. one that when secreted can reach other cells at a distance, the retina shows defects similar to "dry" macular degeneration.
