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Literature for Cisplatin


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  • Researchers clock DNA's recovery time after chemotherapy

    Science Daily. - July 01, 2019

    A team of researchers found that DNA damaged by the widely used chemotherapy drug cisplatin is mostly good as new in noncancerous tissue within two circadian cycles, or two days. The results could inform the development of chronochemotherapies -- strategies aimed at administering chem…

  • A molecular glue to overcome cancer drug resistance?

    Science Daily. - June 07, 2019

    Researchers have discovered a small molecule drug that can stop cancer cells from becoming resistant to chemotherapy. The new compound, which was tested in an animal model of melanoma, could serve as a powerful adjuvant to make current chemotherapies more effective. It works by thwart…

  • Drug makes tumors more susceptible to chemo

    MIT. - June 06, 2019

    Compound that knocks out a DNA repair pathway enhances cisplatin treatment and helps prevent drug-resistance.

  • Cetuximab+RT found to be inferior to standard treatment in HPV+ oropharyngeal cancer

    Science Daily. - August 14, 2018

    An interim analysis of data from a randomized clinical trial of patients with human papillomavirus (HPV)-positive oropharyngeal cancer found that treatment with radiation therapy and cetuximab is associated with worse overall and progression-free survival compared to the current stand…

  • [News] Colorectal adenoma risk in childhood cancer survivors

    Lancet. - March 08, 2018

    Survivors of childhood cancer treated with abdominopelvic radiotherapy, total body irradiation, or cisplatin have an increased risk of developing colorectal adenomas and carcinomas, according to a retrospective cohort study.