1 to 10 of 990 literature results

• Autophagy mitigates metabolic stress and genome damage in mammary tumorigenesis.

  Autophagy is a catabolic process involving self-digestion of cellular organelles during starvation as a means of cell survival; however, if it proceeds to completion, autophagy can lead to cell death ...

  Authors: Vassiliki Karantza-Wadsworth, Shyam Patel, Olga Kravchuk, Guanghua Chen, Robin Mathew, Shengkan Jin, Eileen White

  Source: Genes & development 2007 Jul 1

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• R-type Ca(2+)-channel-evoked CICR regulates glucose-induced somatostatin secretion.

  Pancreatic islets have a central role in blood glucose homeostasis. In addition to insulin-producing beta-cells and glucagon-secreting alpha-cells, the islets contain somatostatin-releasing delta-cell ...

  Authors: Quan Zhang, Martin Bengtsson, Chris Partridge, Albert Salehi, Matthias Braun, Roger Cox, Lena Eliasson, Paul R V Johnson, Erik Renström, Toni Schneider,…

  Source: Nature cell biology 2007 Apr

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• Vitamin C degradation in plant cells via enzymatic hydrolysis of 4-O-oxalyl-L-threonate.

  Increasing the L-ascorbate (vitamin C) content of crops could in principle involve promoting its biosynthesis or inhibiting its degradation. Recent progress has revealed biosynthetic pathways for asco ...

  Authors: Martha A Green, Stephen C Fry

  Source: Nature 2005 Jan 6

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• Metabolite profiling as an aid to metabolic engineering in plants.

  The past decade has seen some impressive successes in the metabolic engineering of biotechnologically important plant pathways. However, plant metabolic engineering currently proceeds more by trial ...

  Authors: Richard N Trethewey

  Source: Current opinion in plant biology 2004 Apr

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• Isoleucine biosynthesis in Leptospira interrogans serotype lai strain 56601 proceeds via a threonine-independent pathway.

  Three leuA-like protein-coding sequences were identified in Leptospira interrogans. One of these, the cimA gene, was shown to encode citramalate synthase (EC 4.1.3.-). The other two encoded alpha-isop ...

  Authors: Hai Xu, Yuzhen Zhang, Xiaokui Guo, Shuangxi Ren, Andreas A Staempfli, Juishen Chiao, Weihong Jiang, Guoping Zhao

  Source: Journal of bacteriology 2004 Aug

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• Genomic islands: tools of bacterial horizontal gene transfer and evolution.

  Bacterial genomes evolve through mutations, rearrangements or horizontal gene transfer. Besides the core genes encoding essential metabolic functions, bacterial genomes also harbour a number ...

  Authors: Mario Juhas, Jan Roelof van der Meer, Muriel Gaillard, Rosalind M Harding, Derek W Hood, Derrick W Crook

  Source: FEMS microbiology reviews 2009 Mar

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• S-box and T-box riboswitches and antisense RNA control a sulfur metabolic operon of Clostridium acetobutylicum.

  The ubiGmccBA operon of Clostridium acetobutylicum is involved in methionine to cysteine conversion. We showed that its expression is controlled by a complex regulatory system combining several RNA-ba ...

  Authors: Gaëlle André, Sergine Even, Harald Putzer, Pierre Burguière, Christian Croux, Antoine Danchin, Isabelle Martin-Verstraete, Olga Soutourina

  Source: Nucleic acids research 2008 Oct

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• Cyclic, pseudocyclic and noncyclic photophosphorylation: new links in the chain.

  Photosynthetic electron transport is coupled to ATP synthesis. This process - photosynthetic phosphorylation - proceeds by several alternative electron-transport pathways in isolated chloroplasts ...

  Authors: John F Allen

  Source: Trends in plant science 2003 Jan

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• MetaPath Online: a web server implementation of the network expansion algorithm.

  We designed a web server for the analysis of biosynthetic capacities of metabolic networks. The implementation is based on the network expansion algorithm and the concept of scopes. For a given ...

  Authors: Thomas Handorf, Oliver Ebenhöh

  Source: Nucleic acids research 2007 Jul

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• A probabilistic generative model for GO enrichment analysis.

  The Gene Ontology (GO) is extensively used to analyze all types of high-throughput experiments. However, researchers still face several challenges when using GO and other functional annotation databas ...

  Authors: Yong Lu, Roni Rosenfeld, Itamar Simon, Gerard J Nau, Ziv Bar-Joseph

  Source: Nucleic acids research 2008 Oct

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