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Garcinol, a polyisoprenylated benzophenone, from the fruit rind of Garcinia spp., has been shown to have anti-inflammatory and anticarcinogenic activities. To study its mechanism of action, we analyze ...
Authors: Jungil Hong, Shengmin Sang, Hye-Jin Park, Seok Joo Kwon, Nanjoo Suh, Mou-Tuan Huang, Chi-Tang Ho, Chung S Yang
Source: Carcinogenesis 2006 Feb
View Full TextActivated astroglial cells produce large amounts of nitric oxide (NO) which, through the binding to soluble guanylyl cyclase, rapidly increases cyclic GMP concentrations. In addition, through ...
Authors: Juan P Bolaños, Angeles Almeida
Source: Antioxidants & redox signaling 2006 May-Jun
View Full TextThe diabetic pathology induces reproductive abnormalities that enhance spontaneous abortion, congenital anomalies and neonatal morbidity/mortality rates, abnormalities that begin with an altered femal ...
Authors: A Jawerbaum, E Gonzalez
Source: Current pharmaceutical design 2005
View Full TextArginine, the only known precursor of nitric oxide, enters the brain parenchyma from the blood through the endothelial cells or from the cerebral spinal fluid through the ependymal cells. Astrocytes ...
Authors: Joann M Gensert, Rajiv R Ratan
Source: Antioxidants & redox signaling 2006 May-Jun
View Full TextIn this review we have analyzed the reactions of nitric oxide (.NO) with superoxide radical (O(2).-) at the vascular compartment which results in limitation of the bioavailability ...
Authors: Natalia Romero, Ana Denicola, Rafael Radi
Source: IUBMB life 2006 Oct
View Full TextWe assessed the redox thiol status influence on nitric oxide (NO) metabolism and efflux in erythrocytes stimulated with acetylcholinesterase substrate (acetylcholine, ACh) and inhibitor (velnacrine ...
Authors: José Pedro Lopes de Almeida, Filomena Almeida Carvalho, Ana Santos Silva-Herdade, Teresa Santos-Freitas, Carlota Saldanha
Source: Cell biology international 2009 Mar
View Full TextSpreading depression (SD) is a wave-like phenomenon that spreads through the gray matter of central nervous tissue. The aim of this work is to investigate how cellular energy supply and nitric oxide ...
Authors: Yuliya A Dahlem, Wolfgang Hanke
Source: Brain research 2005 Jul 5
View Full TextDiscovery of the unexpected intercellular messenger and transmitter nitric oxide (NO) was the highlight of highly competitive investigations to identify the nature of endothelium-derived relaxing ...
Authors: Noboru Toda, Kazuhide Ayajiki, Tomio Okamura
Source: Pharmacological reviews 2007 Mar
View Full TextOnly three biological pathways are known to produce oxygen: photosynthesis, chlorate respiration and the detoxification of reactive oxygen species. Here we present evidence for a fourth pathway, possi ...
Authors: Katharina F Ettwig, Margaret K Butler, Denis Le Paslier, Eric Pelletier, Sophie Mangenot, Marcel M M Kuypers, Frank Schreiber, Bas E Dutilh, Johannes Zedelius, Dirk de Beer,…
Source: Nature 2010 Mar 25
View Full Textapproach to study formation and metabolism of nitric oxide (NO) … ...
Authors: Dimitrios Tsikas, Alexandra Schwarz, Dirk O Stichtenoth
Source: Analytical chemistry 2010 Mar 15
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