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Activated astroglial cells produce large amounts of nitric oxide (NO) which, through the binding to soluble guanylyl cyclase, rapidly increases cyclic GMP concentrations. In addition, through the bind…
Authors: Juan P Bolaños, Angeles Almeida
Source: Antioxidants & redox signaling 2006 May-Jun
View Full TextGarcinol, a polyisoprenylated benzophenone, from the fruit rind of Garcinia spp., has been shown to have anti-inflammatory and anticarcinogenic activities. To study its mechanism of action, we analyze…
Authors: Jungil Hong, Shengmin Sang, Hye-Jin Park, Seok Joo Kwon, Nanjoo Suh, Mou-Tuan Huang, Chi-Tang Ho, Chung S Yang
Source: Carcinogenesis 2006 Feb
View Full TextArginine, the only known precursor of nitric oxide, enters the brain parenchyma from the blood through the endothelial cells or from the cerebral spinal fluid through the ependymal cells. Astrocytes, …
Authors: Joann M Gensert, Rajiv R Ratan
Source: Antioxidants & redox signaling 2006 May-Jun
View Full TextThe diabetic pathology induces reproductive abnormalities that enhance spontaneous abortion, congenital anomalies and neonatal morbidity/mortality rates, abnormalities that begin with an altered femal…
Authors: A Jawerbaum, E Gonzalez
Source: Current pharmaceutical design 2005
View Full TextIn this review we have analyzed the reactions of nitric oxide (.NO) with superoxide radical (O(2).-) at the vascular compartment which results in limitation of the bioavailability of .NO and the forma…
Authors: Natalia Romero, Ana Denicola, Rafael Radi
Source: IUBMB life 2006 Oct
View Full TextWe assessed the redox thiol status influence on nitric oxide (NO) metabolism and efflux in erythrocytes stimulated with acetylcholinesterase substrate (acetylcholine, ACh) and inhibitor (velnacrine ma…
Authors: José Pedro Lopes de Almeida, Filomena Almeida Carvalho, Ana Santos Silva-Herdade, Teresa Santos-Freitas, Carlota Saldanha
Source: Cell biology international 2009 Mar
View Full TextSpreading depression (SD) is a wave-like phenomenon that spreads through the gray matter of central nervous tissue. The aim of this work is to investigate how cellular energy supply and nitric oxide (…
Authors: Yuliya A Dahlem, Wolfgang Hanke
Source: Brain research 2005 Jul 5
View Full TextIn pediatric patients, hyperammonemia can be caused by various acquired or inherited disorders such as urea cycle deficiencies or organic acidemias. The brain is much more susceptible to the deleterio…
Authors: Laurène Cagnon, Olivier Braissant
Source: Brain research reviews 2007 Nov
View Full TextTransgenic alfalfa ( Medicago sativa L.) root cultures expressing sense and antisense barley ( Hordeum vulgare L.) hemoglobin were examined for their ability to metabolize NO. Extracts from lines over…
Authors: Abir U Igamberdiev, Csaba Seregélyes, Nathalie Manac'h, Robert D Hill
Source: Planta 2004 May
View Full TextIn plant cells, as in most eukaryotic organisms, peroxisomes are probably the major sites of intracellular H2O2 production, as a result of their essentially oxidative type of metabolism. Like mitochon…
Authors: Luis A del Río, F Javier Corpas, Luisa M Sandalio, José M Palma, Juan B Barroso
Source: IUBMB life 2003 Feb
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