NextBio

Results presented below are derived from NCBI GEO, EBI ArrayExpress, Broad Institute CMAP 2.0, OMIM and Jackson Laboratory's Mouse Genome Database, as well as additional sources of high-throughput data. High-throughput data retrieved from these sources is curated and processed by NextBio scientists. The results meeting pre-defined significance criteria are imported, and then correlated to all existing study results using NextBio's correlation engine. Green bars viewable under the categories tabs represent the significance of each result's association with the initial concept searched.


T cell differentiation study correlation results

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1 to 10 of 2,391 studies

  • Gene expression profiling of experimental asthma induced by OVA challenge

    score: 100100 | Mus musculus Mus musculus | RNA Expression   RNA Expression

    Three groups of mice (6 mice/group) were sensitized and challenged with allergen (OVA), one group (control group) was sensitized and challenged with placebo (PBS) and served as a control.

    Source: NextBio Library/Immune response and infection

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  • Down-regulation of JunB by RNAi in mouse muscles in vivo

    score: 9393 | Mus musculus Mus musculus | RNA Expression   RNA Expression

    Mouse adult tibialis anterior muscles were transfected with vectors expressing shRNA against JunB or scramble. 4 muscles were used for each condition. Mice were sacrificed 12 days later and total RNA was extracted

    Source: NextBio Library/Metabolic disorders and Obesity

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  • Effects of microRNA-155 and EBV-infection

    score: 9191 | Homo sapiens Homo sapiens | RNA Expression   RNA Expression

    The EBV positive Burkitt's lymphoma cell line, Akata was infected with a control or a microRNA-155 expressing retrovirus, or EBV positive and EBV negative Burkitt's lymphoma cells were compared.

    Organization: Tulane Health Sciences Center Pathology 1430 Tulane Ave., SL79 New Orleans LA 70112 Country United States

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  • Transcriptome modulation analysis of CMV-infected monocyte-derived dendritic cells

    score: 9191 | Homo sapiens Homo sapiens | RNA Expression   RNA Expression

    Immature monocyte-derived dendritic cells were generated from CMV neg healthy blood donors and infected or not with an endotheliotropic CMV strain. Gene expression modulation by the CMV infection was studied in a time course assay (non-infected - NI - vs 6h or 48h post-infection.

    Authors: Haspot Fabienne, Bihouée Audrey, Chevalier Catherine, Houlgatte Rémi, Halary Franck

    Organization: INSERM UMR643 ITERT - CHU Hotel Dieu 30, bd Jean Monnet Nantes 44093 Country FRANCE

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  • microRNA-155 in EBV-regulated gene expression

    score: 8585 | Homo sapiens Homo sapiens | RNA Expression   RNA Expression

    microRNA-155 is an Epstein-Barr Virus induced gene that modulates EBV-regulated gene expression (EBV infection)

    Authors: Yin Q, McBride J, Fewell C, Lacey M, Wang X, Lin Z et al.

    Organization: Tulane Health Sciences Center Pathology 1430 Tulane Ave., SL79 New Orleans LA 70112 Country United States

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  • Estrogen response in mice lacking Estrogen Receptor (ER)-alpha by exon 3 deletion of ERalpha

    score: 8383 | Mus musculus Mus musculus | RNA Expression   RNA Expression

    Knockouts for estrogen receptor (ER)-alpha were generated by exon 3 deletion of the ERalpha gene, and confirmed to lack residual alternative splice-variants. WT and KO mice were ovariectomized, intraperitoneally injected with saline or 250ng per 100uL estradiol, and analyzed 2 and 24hrs later.

    Source: NextBio Library/Mutation and Phenotypic data

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  • Kidney from patients with normal and dysfunctional renal allografts

    score: 7373 | Homo sapiens Homo sapiens | RNA Expression   RNA Expression

    We used DNA microarrays in a systematic study of gene-expression patterns in biopsy samples from normal and dysfunctional renal allografts.

    Authors: Sarwal Minnie

    Organization: Stanford University Biochemistry Brown Stanford CA 94305 Country USA

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  • Sex-dependent and HNF4alpha-dependent Mouse Liver Gene Expression

    score: 7070 | Mus musculus Mus musculus | RNA Expression   RNA Expression

    Hepatocyte nuclear factor (HNF4alpha) is a liver-enriched transcription factor that regulates numerous liver-expressed genes. Presently, a liver-specific HNF4alpha-deficient mouse model was used to characterize the impact of liver HNF4alpha deficiency in female and male mice.

    Authors: Holloway G Minita, Miles D Gregory, Dombkowski A Alan, Waxman J David

    Organization: Boston University Department of Biology 5 Cummington St Boston MA 02135 Country USA

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  • Gene expression profile of basal signaling in T cells.

    score: 6666 | Homo sapiens Homo sapiens | RNA Expression   RNA Expression

    Ligand independent basal signal controlling gene expression profiles in the Jurkat T cell line and mouse thymocytes

    Authors: 14624253

    Organization: Stanford Microarray Database (SMD) E-mail(s) array@genome.stanford.edu Phone 650-498-6012 URL http://genome-www5.stanford.edu/ Stanford University, School of Medicine 300 Pasteur Drive Stanford CA 94305 Country USA

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  • Gene expression profiling induced by overexpression and silencing of Ankrd2

    score: 6161 | Mus musculus Mus musculus | RNA Expression   RNA Expression

    Ankrd2 is a member of the Muscle Ankyrin Repeat Protein family (MARPs). We produced and examined both morphological and functional features of myocytes stable overexpressing or silencing the Ankrd2 protein.

    Authors: Bean C, Facchinello N, Salamon M, Faulkner G, Lanfranchi G

    Organization: University of Padova CRIBI - Biotechnology Center and Biology Department Genomic Research Group Via U. Bassi, 58/B Padova 35131 Country Italy

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