1 to 10 of 84 studies

• Rapamycin and Akt-dependent prostate intraepithelial neoplasia

  Mus musculus |   RNA Expression

  Transgenic (Probasin driven Myr-AKT)or wild-type littermates were treated with Rapamycin (RAD001) or placebo and sacrificed at 12 and 48 hours following the beginning of treatment

  Authors: Majumder PK, Febbo PG, Bickoff R, Berger R, Xue Q, McMahon LM et al.

  Organization: Dana-Farber Cancer Institute Medical Oncology Golub and Sellers 44 Binney St. Boston MA 02115 Country USA

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• Neurocrine Body Atlas Hs: Relative gene expression

  Homo sapiens |   RNA Expression

  Normal human tissue samples from ten post-mortem donors were processed to generate total RNA, which was subsequently analyzed for gene expression using Affymetrix U133 plus 2.0 arrays. Donor information: Donor 1 - 25 year old male; donor 2 - 38 year old male; donor 3 - 39 year old female; donor 4 - …

  Authors: Roth RB

  Organization: Neurocrine Biosciences, Inc. Molecular Medicine 12790 El Camino Real San Diego CA 92130 Country USA

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• GNF Body Atlas Hs: Relative gene expression

  Homo sapiens |   RNA Expression

  The tissue-specific pattern of mRNA expression can indicate important clues about gene function. High-density oligonucleotide arrays offer the opportunity to examine patterns of gene expression on a genome scale. Toward this end, we have designed custom arrays that interrogate the expression of the …

  Authors: Su AI, Wiltshire T, Batalov S, Lapp H, Ching KA, Block D et al.

  Organization: Genomics Institute of the Novartis Research Foundation RNA Profiling Group 10675 John Jay Hopkins San Diego CA 92121 Country USA

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• Prostate Atlas Hs: Relative gene expression

  Homo sapiens |   RNA Expression

  Luminal, basal, stromal, and endothelial cells were MACS sorted from whole tissue. Targets from five biological replicates of each were generated and the expression profiles were determined using Affymetrix U133 Plus 2.0 arrays. These data represent cell specific transcriptomes.

  Authors: Oudes AJ, Liu AY

  Organization: Institute for Systems Biology 1441 N 34th St. Seattle WA 98103 Country USA

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• GNF Body Atlas Mm: Relative gene expression

  Mus musculus |   RNA Expression

  (Abstract) The tissue-specific pattern of mRNA expression can indicate important clues about gene function. High-density oligonucleotide arrays offer the opportunity to examine patterns of gene expression on a genome scale. Toward this end, we have designed custom arrays that interrogate the express…

  Authors: Su AI, Wiltshire T, Batalov S, Lapp H, Ching KA, Block D et al.

  Organization: Genomics Institute of the Novartis Research Foundation RNA Profiling Group 10675 John Jay Hopkins San Diego CA 92121 Country USA

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• Protein 4.1B suppresses prostate cancer progression and metastasis

  Homo sapiens |   RNA Expression

  In a screen for genes involved with prostate cancer metastasis, we found that 4.1B expression is reduced in highly metastatic tumors. Protein 4.1B is a 4.1/ezrin/radixin/moesin (FERM) domain-containing protein whose expression is frequently lost in a variety of human tumors, including meningiomas, …

  Authors: Wong S, Haack H, Shen SS, Whittaker CA, Hynes RO

  Organization: MIT 77 mass ave cambridge MA 02139 Country USA

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• LNCaP treatment of cells with DHT and a sequence-specific DNA binding polyamide

  Homo sapiens |   RNA Expression

  Androgen Receptor (AR) is essential for the growth and progression of prostate cancer in both hormone-sensitive and hormone-refractory disease. We have designed a sequence-specific DNA binding polyamide (1) that targets the consensus androgen response element (ARE). This polyamide binds the PSA prom…

  Authors: Dervan PB, Nickols NG

  Organization: California Institute of Technology 1200 East California Blvd Pasadena CA 91125 Country USA

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• Expression data from murine ventral prostate treated with placebo or RAD001

  Mus musculus |   RNA Expression

  A mTOR depedent and a phenotype dependent sigature can be identified.

  Authors: Xu Q, Ross K, Sellers W, Golub T

  Organization: dana farber cancer institute Medical Oncology sellers 44 binney st boston MA 02115 Country USA

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• Genes regulated by the processed form of AIbZIP/CREB3L4

  Homo sapiens |   RNA Expression

  Androgen-induced bZIP (AIbZIP) is a basic leucine zipper (bZIP)

  Authors: Labrie Claude, Calvo Ezequiel

  Organization: CRCHUL Molecular Endocrinilogy Microarrays 2705 Boul. Laurier Quebec Quebec G1V 4G2 Country Canada

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• Expression data from LNCaP cell line

  Homo sapiens |   RNA Expression

  Androgen receptor (AR) is a ligand-dependent transcription factor that plays a key role in the onset and progression of prostate cancer. Surprisingly little is known of AR binding sites and collaborating transcription factors in the human genome. Here we have identified the DNA sequence motifs that …

  Authors: Wang Qianben, Li Wei

  Organization: Dana Farber Cancer Institute 44 Binney Street Boston MA 02115 Country USA

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