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Results presented below are derived from NCBI GEO, EBI ArrayExpress, Broad Institute CMAP 2.0, OMIM and Jackson Laboratory's Mouse Genome Database, as well as additional sources of high-throughput data. High-throughput data retrieved from these sources is curated and processed by NextBio scientists. The results meeting pre-defined significance criteria are imported, and then correlated to all existing study results using NextBio's correlation engine. Green bars viewable under the categories tabs represent the significance of each result's association with the initial concept searched.


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Lupus related studies

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1 to 9 of 9 studies

  • PBMC profile of juvenile idiopathic arthritis, systemic lupus erythematosus, and PAPA syndrome

    Homo sapiens Homo sapiens | RNA Expression   RNA Expression

    123 RNA samples from patients with Systemic onset Juvenile Idiopathic Arthritis (SoJIA) with or without systemic symptoms, systemic lupus erythematosus (SLE), and PAPA syndrome.

    Authors: Allantaz F, Chaussabel D, Stichweh D, Bennett L, Allman W, Mejias A et al.

    Organization: Baylor Institute for Immunology Research 3434 Live Oak Street Dallas TX 75204 Country USA

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  • Mouse Phenotypes - Autoimmune disease

    Mus musculus Mus musculus | Mutations/Phenotypic   Mutations/Phenotypic

    This study contains curated mouse gene mutation data extracted from the Mouse Genome Database (MGD) at The Jackson Laboratory, Bar Harbor, Maine. Additional computational processing and curation of mouse phenotype data was performed to further organize and group data from related phenotypes into uni…

    Source: NextBio Library/Mutation and Phenotypic data

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  • Congenic strains containing overlapping BXSB intervals reveal novel lupus candidate genes

    Mus musculus Mus musculus | RNA Expression   RNA Expression

    To probe the genetic basis of systemic lupus erythematosus in BXSB mice, several congenic strains of mice were profiled by microarray.

    Source: NextBio Library/Immune response and infection

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  • OMIM - Autoimmune disease

    Homo sapiens Homo sapiens | Mutations/Phenotypic   Mutations/Phenotypic

    This study contains curated human phenotype data extracted from OMIM. Additional computational processing and curation of the phenotype data was performed to further organize and group data from related phenotypes into unifying disease categories.

    Source: NextBio Library/Mutation and Phenotypic data

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  • Study of systemic lupus erythematosus

    Homo sapiens Homo sapiens | RNA Expression   RNA Expression

    This study was designed to determine whether specific lymphocyte and myeloid subsets freshly isolated from the blood of systemic lupus erythematosus patients demonstrated unique gene expression profiles compared to subsets isolated from healthy controls.

    Authors: Davis L

    Organization: UT Southwestern Medical Center Internal Medicine Davis 5323 Harry Hines Blvd Dallas TX 75390-8884 Country United States

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  • T-cells from SLE patients and healthy donors with or without stimulation with nitric oxide and TCR.

    Homo sapiens Homo sapiens | RNA Expression   RNA Expression

    Gene expresssion analysis of T-cells from SLE patients and healthy donors with or without stimulation with nitric oxide and TCR.

    Authors: Fernandez DR, Telarico T, Bonilla E, Li Q, Banerjee S, Middleton FA et al.

    Organization: SUNY Upstate Medical Univ Neuroscience and Physiology 750 East Adams St Syracuse NY 13210 Country USA

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  • Male and female BWF1 lupus-prone mice

    Mus musculus Mus musculus | RNA Expression   RNA Expression

    Whole spleen was taken from pre-lupus (4 months old) BWF1 (females are lupus-prone) male and female mice.

    Authors: Gubbels R Melanie, Kotzin L Brian

    Organization: University of Colorado Health Sciences Center Denver CO 80262 Country USA

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  • Modular analysis framework for blood genomics studies

    Homo sapiens Homo sapiens | RNA Expression   RNA Expression

    The analysis of patient blood transcriptional profiles offers a means to investigate the immunological mechanisms relevant to human diseases on a genome-wide scale. In addition, such studies provide a basis for the discovery of clinically relevant biomarker signatures.

    Authors: Chaussabel D, Quinn C, Shen J, Patel P, Glaser C, Baldwin N et al.

    Organization: Baylor Institute for Immunology Research 3434 Live Oak Dallas TX 75204 Country USA

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  • B cells and CD4 T cells from healthy, SLE, and rheumatoid arthritis patients

    Homo sapiens Homo sapiens | RNA Expression   RNA Expression

    CD4 T and B cells were sorted by flow cytometry from PBMC of patients with SLE, RA and healthy controls. GeneChip® Human genome U133 Plus 2.0 arrays were hybridized in monoplicates.

    Authors: Lauwerys R Bernard, Louahed Jamila, Knoops Laurent, Maudoux Anne-Lise, Wakeland K Edward, Van den Eynde J Benoit et al.

    Organization: Université catholique de Louvain Internal Medicine Rheumatology Unit Avenue Hippocrate 10 Brussels 1200 Country Belgium

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