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Results presented below are derived from NCBI GEO, EBI ArrayExpress, Broad Institute CMAP 2.0, OMIM and Jackson Laboratory's Mouse Genome Database, as well as additional sources of high-throughput data. High-throughput data retrieved from these sources is curated and processed by NextBio scientists. The results meeting pre-defined significance criteria are imported, and then correlated to all existing study results using NextBio's correlation engine. Green bars viewable under the categories tabs represent the significance of each result's association with the initial concept searched.


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Imatinib related studies

1 to 3 of 3 studies

  • Liver Pharmacology and Xenobiotic Response Repertoire

    Rattus norvegicus Rattus norvegicus | RNA Expression   RNA Expression

    A definition of RNA expression changes that correlate with liver response programs and an understanding of the similarities and differences in responses to different classes of chemicals would aid in new chemical or drug characterization and add to our understanding of liver biology.

    Authors: Natsoulis G, Pearson CI, Gollub J, Eynon B, Ferng J, Nair R et al.

    Organization: Iconix Biosciences 325 E. Middlefield Rd. Mountain View CA 94043 USA

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  • Lung cancer cells + dasatinib, imatinib, nilotinib or PD0325901

    Homo sapiens Homo sapiens | RNA Expression   RNA Expression

    A549 human lung cancer cell line was treated with 4 kinase inhibitors for 4 or 20 hours. A dilution series for the compounds was also used.

    Source: NextBio Library/Pharmacology and Toxicology

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  • Drug target sets for approved compounds

    Homo sapiens Homo sapiens | Therapeutic   Therapeutic

    The DrugBank database is a unique bioinformatics and cheminformatics resource that combines detailed drug (i.e. chemical, pharmacological and pharmaceutical) data with comprehensive drug target (i.e. sequence, structure, and pathway) information.

    Authors: David S Wishart, Craig Knox, An Chi Guo, Dean Cheng, Savita Shrivastava, Dan Tzur et al.

    Organization: Department of Computing Science, University of Alberta

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