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Results presented below are derived from NCBI GEO, EBI ArrayExpress, Broad Institute CMAP 2.0, OMIM and Jackson Laboratory's Mouse Genome Database, as well as additional sources of high-throughput data. High-throughput data retrieved from these sources is curated and processed by NextBio scientists. Click on the study title to see individual experiments comprising the study. Click the 'Full Study Details' link to find more information about this study.

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  • NOTCH signaling in T-cell acute lymphoblastic leukemia

    Homo sapiens Homo sapiens

    In T-cell acute lymphoblastic leukemia (T-ALL) NOTCH 1 receptors are frequently mutated. This leads to aberrantly high Notch signaling, but how this translates into deregulated cell cycle control and the transformed cell type is poorly understood. In this report, we analyze downstream responses resu…

    Authors: Dohda T, Maljukova A, Liu L, Heyman M, Grandér D, Brodin D et al.

    Organization: Karolinska Institute Department of biosciences and Nutrition Affymetrix lab Halsovagen 7-9 Stockholm S-141 57 Huddinge Country Sweden

    Total # Biosets: 1

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