1 to 10 of 1,697 studies

• Mouse Phenotypes - Neoplasms

  score: 100 | Mus musculus |   Mutations/Phenotypic

  This study contains curated mouse gene mutation data extracted from the Mouse Genome Database (MGD) at The Jackson Laboratory, Bar Harbor, Maine. Additional computational processing and curation of mouse phenotype data was performed to further organize and group data from related phenotypes into uni…

  Source: NextBio Library/Mutation and Phenotypic data

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• Cancer census - gene mutations in cancer and other diseases

  score: 100 | Homo sapiens |   Mutations/Phenotypic

  The Cancer Gene Census is an ongoing effort to catalogue those genes for which mutations have been causally implicated in cancer. The original census and analysis was published in Nature Reviews Cancer

  Authors: P Andrew Futreal, Lachlan Coin, Mhairi Marshall, Thomas Down, Timothy Hubbard, Richard Wooster et al.

  Organization: Cancer Genome Project, Human Genome Analysis Group and Pfam Group, Wellcome Trust Sanger Institute

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• Liver Pharmacology and Xenobiotic Response Repertoire

  score: 100 | Rattus norvegicus |   RNA Expression

  A definition of RNA expression changes that correlate with liver response programs and an understanding of the similarities and differences in responses to different classes of chemicals would aid in new chemical or drug characterization and add to our understanding of liver biology.

  Authors: Natsoulis G, Pearson CI, Gollub J, Eynon B, Ferng J, Nair R et al.

  Organization: Iconix Biosciences 325 E. Middlefield Rd. Mountain View CA 94043 USA

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• Identification of transcripts regulated by RNA helicase A in Chlorocebus athiops

  score: 100 | Macaca mulatta |   RNA Expression

  Identification of transcripts regulated by RNA helicase A using siRNA and coimmunoprecipitation.

  Source: NextBio Library/Metabolic disorders and Obesity

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• SV40 T antigen in the mouse small intestine epithelium

  score: 100 | Mus musculus |   RNA Expression

  We have performed a microarray analysis to examine the global gene expression changes induced by wild-type and mutant SV40 TAg linked to specific transforming functions.

  Source: NextBio Library/Oncology

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• Delipidation of white adipose tissue of mice fed conjugated linoleic acid

  score: 99 | Mus musculus |   RNA Expression

  he white adipose tissue (WAT) rapidly loses mass when mice are fed a diet containing trans-10, cis-12 conjugated linoleic acid (t10c12 CLA). A microarray analysis of WAT due to CLA feeding was performed to better define the processes and genes involved.

  Authors: LaRosa CP, Miner J, Xia Y, Fromm ME, Kachman S

  Organization: University of Nebraska, Lincoln Center of Biotechnology 19th & Vine Lincoln NE 68588-0665 Country USA

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• OMIM - Malignant neoplasms

  score: 99 | Homo sapiens |   Mutations/Phenotypic

  This study contains curated human phenotype data extracted from OMIM. Additional computational processing and curation of the phenotype data was performed to further organize and group data from related phenotypes into unifying disease categories.

  Source: NextBio Library/Mutation and Phenotypic data

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• Broad Connectivity Map (CMAP 2.0) compound database

  score: 99 | Homo sapiens |   RNA Expression

  A reference collection of genome-wide transcriptional expression data from cultured human cells treated with bioactive small molecules that enable the discovery of functional connections between drugs, genes and diseases through the transitory feature of common gene-expression changes.

  Authors: Lamb J

  Organization: Broad Institute Seven Cambridge Center Cambridge MA 02142 USA

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• Murine host cell response to Aeromonas infection

  score: 99 | Mus musculus |   RNA Expression

  Aims: To assess the virulence of multiple Aeromonas spp. using two models, a neonatal mouse assay and a mouse intestinal cell culture.

  Authors: Hayes L Samuel, Vesper J Stephen, Rodgers R Mark, Lye J Dennis, Stelma N Gerard

  Organization: United States Environmental Protection Agency MS-387 NRMRL/WSWRD 26 W. Martin Luther King Dr. Cincinnati OH 45268 Country USA

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• Murine T cell response to IL-2 treatment

  score: 99 | Mus musculus |   RNA Expression

  The cytokine IL-2 determines T cell fate by controlling T cell proliferation and differentiation, but the expression files of IL-2 regulated genes are not defined

  Authors: Zhang Zhaoduo, Martino Anthony, Faulon Jean-Loup

  Organization: Sandia National Labs Biosystems 7011 East Ave Livermore CA 94551 Country USA

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