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PubChem
Name: Serine
PubChem Compound ID: 5951
Description: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
Molecular formula: C3H7NO3
Molecular weight: 105.093 g/mol
Synonyms:
C00065; L-Serine, homopolymer; Serine (VAN); 25821-52-7; Propanoic acid, 2-amino-3-hydroxy-, (S)-; L-Serine (JAN); L-ser; 2-Amino-3-hydroxypropanoic acid, (S)-; Polyserine; 2-Amino-3-hydroxypropionic acid.
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DrugBank
Identification
Name: Serine
Name (isomeric): DB00133
Drug Type: small molecule
Description: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
Synonyms:
2-Amino-3-hydroxypropionic acid; Serine; (S)-Serine; 3-Hydroxyalanine; L-3-Hydroxy-2-aminopropionic acid; (-)-Serine; L-Ser; L-(-)-Serine; (S)-a-Amino-b-hydroxypropionic acid; (S)-2-Amino-3-hydroxypropanoic acid.
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Category: Micronutrient, Dietary supplement, Non-Essential Amino Acids
CAS number: 56-45-1
Pharmacology
Indication: Used as a natural moisturizing agent in some cosmetics and skin care products.
Pharmacology:
Serine is classified as a nutritionally non-essential amino acid. Serine is critical for the production of the body's proteins, enzymes and muscle tissue. Serine is needed for the proper metabolism of fats and fatty acids. It also helps in the production of antibodies. Serine is used as a natural moisturizing agent in some cosmetics and skin care p...
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Mechanism of Action:
L-Serine plays a role in cell growth and development (cellular proliferation). The conversion of L-serine to glycine by serine hydroxymethyltransferase results in the formation of the one-carbon units necessary for the synthesis of the purine bases, adenine and guanine. These bases when linked to the phosphate ester of pentose sugars are essential ...
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Affected organisms: Humans and other mammals

Targets


Transporters