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QuickView for SLCO1B1 (gene)


Gene Symbol:
SLCO1B1 Homo sapiens Homo sapiens
Full name:
solute carrier organic anion transporter family, member 1B1
Synonyms:
MGC133282, OATP-2, OATP-C, OATP1B1, OATP2, OATPC, LST-1, LST1, liver-specific organic anion transporter 1, HBLRR, SLC21A6, sodium-independent organic anion-transporting polypeptide 2, solute carrier family 21 (organic anion transporter), member 6, solute carrier family 21 member 6, solute carrier organic anion transporter family member 1B1, solute carrier organic anion transporter family, member 1B1
Genomic Location:
Chr 12: 21175404-21283997
Description:
This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of numerous endogenous compounds including bilirubin, 17-beta-glucuronosyl estradiol and leukotriene C4. This protein is also involved in the removal of drug compounds such as...
Orthologs:
Macaca mulatta Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 12
12p


Transcripts Names
NM_006446



GO Molecular Function

organic anion transmembrane transporter activity | anion transmembrane transporter activity | transmembrane transporter activity | active transmembrane transporter activity | transporter activity | ion transmembrane transporter activity | substrate-specific transmembrane transporter activity | secondary active transmembrane transporter activity | substrate-specific transporter activity | sodium-independent organic anion transmembrane transporter activity

GO Biological Process

organic anion transmembrane transporter activity | establishment of localization | anion transmembrane transporter activity | cellular process | monocarboxylic acid transport | localization | anion transport | transmembrane transporter activity | organic cyclic compound metabolic process | oxoacid metabolic process | monocarboxylic acid metabolic process | transport | lipid metabolic process | ion transmembrane transport | organic substance transport | active transmembrane transporter activity | small molecule metabolic process | transporter activity | organic acid transport | ion transmembrane transporter activity | cellular ketone metabolic process | organic anion transport | substrate-specific transmembrane transporter activity | carboxylic acid metabolic process | bile acid metabolic process | sodium-independent organic anion transport | metabolic process | primary metabolic process | bile acid and bile salt transport | organic substance metabolic process | secondary active transmembrane transporter activity | substrate-specific transporter activity | steroid metabolic process | transmembrane transport | organic acid metabolic process | carboxylic acid transport | ion transport | cellular metabolic process | sodium-independent organic anion transmembrane transporter activity

GO Cellular Component

integral to membrane | plasma membrane part | cell | intrinsic to membrane | plasma membrane | membrane part | integral to plasma membrane | cell part | cell periphery | basolateral plasma membrane | membrane | intrinsic to plasma membrane