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QuickView for SLC22A8 (gene)


Gene Symbol:
SLC22A8 Homo sapiens Homo sapiens
Full name:
solute carrier family 22 (organic anion transporter), member 8
Synonyms:
MGC24086, organic anion transporter 3, OAT3, hOAT3, solute carrier family 22 (organic anion transporter), member 8, solute carrier family 22 member 8
Genomic Location:
Chr 11: 62516872-62539887
Description:
The protein encoded by this gene is involved in the sodium-independent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and appears to be localized to the basolateral membrane of the kidney. [provided by RefSeq]
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Bos taurus Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 11
11q11





GO Molecular Function

inorganic anion exchanger activity | kinase binding | organic anion transmembrane transporter activity | anion transmembrane transporter activity | protein kinase binding | enzyme binding | transmembrane transporter activity | amine transmembrane transporter activity | binding | anion:anion antiporter activity | protein kinase C binding | cation transmembrane transporter activity | antiporter activity | active transmembrane transporter activity | transporter activity | ion transmembrane transporter activity | substrate-specific transmembrane transporter activity | organic cation transmembrane transporter activity | protein binding | secondary active transmembrane transporter activity | substrate-specific transporter activity | inorganic cation transmembrane transporter activity | quaternary ammonium group transmembrane transporter activity

GO Biological Process

inorganic anion exchanger activity | organic anion transmembrane transporter activity | establishment of localization | oligopeptide transport | anion transmembrane transporter activity | organic cation transport | cellular process | localization | anion transport | transmembrane transporter activity | response to stimulus | response to chemical stimulus | transport | amine transmembrane transporter activity | amine transport | anion:anion antiporter activity | ion transmembrane transport | organic substance transport | cation transmembrane transporter activity | antiporter activity | active transmembrane transporter activity | response to methotrexate | peptide transport | transporter activity | organic acid transport | ion transmembrane transporter activity | glutathione transport | nitrogen compound transport | organic anion transport | response to toxin | substrate-specific transmembrane transporter activity | organic cation transmembrane transporter activity | tripeptide transport | amino acid transport | response to organic substance | modified amino acid transport | secondary active transmembrane transporter activity | substrate-specific transporter activity | transmembrane transport | inorganic cation transmembrane transporter activity | response to organic cyclic compound | carboxylic acid transport | cation transport | quaternary ammonium group transport | ion transport | quaternary ammonium group transmembrane transporter activity

GO Cellular Component

integral to membrane | plasma membrane part | cell | intrinsic to membrane | plasma membrane | membrane part | cell part | cell periphery | basolateral plasma membrane | membrane