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QuickView for SLC22A6 (gene)


Gene Symbol:
SLC22A6 Homo sapiens Homo sapiens
Full name:
solute carrier family 22 (organic anion transporter), member 6
Synonyms:
OAT1, organic anion transporter 1, PAH transporter, PAHT, para-aminohippurate transporter, MGC45260, ROAT1, solute carrier family 22 (organic anion transporter), member 6, solute carrier family 22 member 6, renal organic anion transporter 1, HOAT1, hPAHT, hROAT1, FLJ55736
Genomic Location:
Chr 11: 62500645-62509045
Description:
The protein encoded by this gene is involved in the sodium-dependent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and may be localized to the basolateral membrane. Four transcript variants encoding four different isoforms have been found for this gene. [provided ...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Bos taurus Pan troglodytes Canis lupus familiaris
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 11
11q12.3





GO Molecular Function

inorganic anion exchanger activity | organic anion transmembrane transporter activity | anion transmembrane transporter activity | transmembrane transporter activity | binding | anion:anion antiporter activity | antiporter activity | active transmembrane transporter activity | transporter activity | ion transmembrane transporter activity | substrate-specific transmembrane transporter activity | protein binding | secondary active transmembrane transporter activity | substrate-specific transporter activity | sodium-independent organic anion transmembrane transporter activity

GO Biological Process

inorganic anion exchanger activity | organic anion transmembrane transporter activity | establishment of localization | anion transmembrane transporter activity | renal tubular secretion | cellular process | secretion | localization | dicarboxylic acid transport | anion transport | transmembrane transporter activity | response to stimulus | response to chemical stimulus | transport | anion:anion antiporter activity | ion transmembrane transport | organic substance transport | alpha-ketoglutarate transport | antiporter activity | single-organism process | active transmembrane transporter activity | response to methotrexate | transporter activity | organic acid transport | ion transmembrane transporter activity | organic anion transport | substrate-specific transmembrane transporter activity | system process | sodium-independent organic anion transport | response to organic substance | renal system process | secondary active transmembrane transporter activity | substrate-specific transporter activity | transmembrane transport | response to organic cyclic compound | carboxylic acid transport | single-multicellular organism process | ion transport | sodium-independent organic anion transmembrane transporter activity | multicellular organismal process

GO Cellular Component

integral to membrane | plasma membrane part | cell | intrinsic to membrane | macromolecular complex | plasma membrane | membrane raft | membrane part | integral to plasma membrane | cell part | cell periphery | basolateral plasma membrane | caveola | membrane | protein complex | intrinsic to plasma membrane